Human IL10/CSIF/GVHDS ORF/cDNA clone-Lentivirus plasmid (NM_000572)

Cat. No.: pGMLP-IL-013
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human IL10/CSIF/GVHDS Lentiviral expression plasmid for IL10 lentivirus packaging, IL10 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP-IL-013
Gene Name IL10
Accession Number NM_000572
Gene ID 3586
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 537 bp
Gene Alias CSIF,GVHDS,IL-10,IL10A,TGIF
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGCACAGCTCAGCACTGCTCTGTTGCCTGGTCCTCCTGACTGGGGTGAGGGCCAGCCCAGGCCAGGGCACCCAGTCTGAGAACAGCTGCACCCACTTCCCAGGCAACCTGCCTAACATGCTTCGAGATCTCCGAGATGCCTTCAGCAGAGTGAAGACTTTCTTTCAAATGAAGGATCAGCTGGACAACTTGTTGTTAAAGGAGTCCTTGCTGGAGGACTTTAAGGGTTACCTGGGTTGCCAAGCCTTGTCTGAGATGATCCAGTTTTACCTGGAGGAGGTGATGCCCCAAGCTGAGAACCAAGACCCAGACATCAAGGCGCATGTGAACTCCCTGGGGGAGAACCTGAAGACCCTCAGGCTGAGGCTACGGCGCTGTCATCGATTTCTTCCCTGTGAAAACAAGAGCAAGGCCGTGGAGCAGGTGAAGAATGCCTTTAATAAGCTCCAAGAGAAAGGCATCTACAAAGCCATGAGTGAGTTTGACATCTTCATCAACTACATAGAAGCCTACATGACAATGAAGATACGAAACTGA
ORF Protein Sequence MHSSALLCCLVLLTGVRASPGQGTQSENSCTHFPGNLPNMLRDLRDAFSRVKTFFQMKDQLDNLLLKESLLEDFKGYLGCQALSEMIQFYLEEVMPQAENQDPDIKAHVNSLGENLKTLRLRLRRCHRFLPCENKSKAVEQVKNAFNKLQEKGIYKAMSEFDIFINYIEAYMTMKIRN

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T09092-Ab Anti-IL10/ CSIF/ GVHDS functional antibody
    Target Antigen GM-Tg-g-T09092-Ag IL10 protein
    Cytokine cks-Tg-g-GM-T09092 interleukin 10 (IL10) protein & antibody
    ORF Viral Vector pGMLV001166 Human IL-10 Lentivirus plasmid
    ORF Viral Vector pGMAD000014 Human IL10 Adenovirus plasmid
    ORF Viral Vector pGMAP000484 Human IL10 Adenovirus plasmid
    ORF Viral Vector pGMLP-IL-013 Human IL10 Lentivirus plasmid
    ORF Viral Vector pGMAP-IL-096 Human IL10 Adenovirus plasmid
    ORF Viral Vector pGMPC004770 Human IL10 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLV001166 Human IL-10 Lentivirus particle
    ORF Viral Vector vGMAD000014 Human IL10 Adenovirus particle
    ORF Viral Vector vGMAP000484 Human IL10 Adenovirus particle
    ORF Viral Vector vGMLP-IL-013 Human IL10 Lentivirus particle
    ORF Viral Vector vGMAP-IL-096 Human IL10 Adenovirus particle


    Target information

    Target ID GM-T09092
    Target Name IL-10/IL10
    Gene Group Identifier
    （Target Gene ID in Homo species)         		3586
    Gene ID 100034187 (Equus caballus), 16153 (Mus musculus), 25325 (Rattus norvegicus), 281246 (Bos taurus)
    3586 (Homo sapiens), 403628 (Canis lupus familiaris), 493683 (Felis catus), 694931 (Macaca mulatta)
    Gene Symbols & Synonyms IL10,Il10,IF2A,IL-10,CSIF,If2a,Il-10,IL10X,TGIF,GVHDS,IL10A
    Target Alternative Names CSIF,Cytokine synthesis inhibitory factor (CSIF),GVHDS,IF2A,IL-10,IL10,IL10A,IL10X,If2a,Il-10,Il10,Interleukin-10,TGIF
    Uniprot Accession P18893,P22301,P29456,P43480,P48411,P51496,P55029,Q28374
    Additional SwissProt Accessions: Q28374,P18893,P29456,P43480,P22301,P48411,P55029,P51496
    Uniprot Entry Name
    Protein Sub-location Secreted Protein/Potential Cytokines
    Category Therapeutics Target, Immuno-oncology Target, Cytokine Target
    Disease cancer, Ovary Cancer, metastases, asthma, Malignant neoplasm of bladder
    Disease from KEGG Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, FoxO signaling pathway, C-type lectin receptor signaling pathway, JAK-STAT signaling pathway, T cell receptor signaling pathway, Intestinal immune network for IgA production, Pertussis, Yersinia infection, Leishmaniasis, Chagas disease, African trypanosomiasis, Malaria, Toxoplasmosis, Amoebiasis, Staphylococcus aureus infection, Tuberculosis, Asthma, Autoimmune thyroid disease, Inflammatory bowel disease, Allograft rejection
    Gene Ensembl ENSMUSG00000016529, ENSBTAG00000006685, ENSG00000136634, ENSCAFG00845001289, ENSMMUG00000023569
    Target Classification Checkpoint-Immuno Oncology


    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.