Human HLA-DRB1/HLA-DR1B ORF/cDNA clone-Adenovirus plasmid (BC031023)

Cat. No.: pGMAP000274
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human HLA-DRB1/HLA-DR1B adenoviral expression plasmid for HLA-DRB1 adenovirus packaging, HLA-DRB1 adenovirus.

Our GM-Adenovirus vector is optimized with the GMVC-modified Adeasy adenovirus packaging system. Find more about the GMVC-modified adenovirus packaging system.

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Product Description

Catalog ID pGMAP000274
Gene Name HLA-DRB1
Accession Number BC031023
Gene ID 3123
Species Human
Product Type Adenovirus plasmid (overexpression)
Insert Length 801 bp
Gene Alias HLA-DR1B
Fluorescent Reporter GFP
Mammalian Cell Selection Null
Fusion Tag 3xflag (C-Terminal)
Promoter EF1
Resistance Kanamycin
ORF Nucleotide Sequence ATGGTGTGTCTGAGGCTCCCTGGAGGCTCCTGCATGGCAGTTCTGACAGTGACACTGATGGTGCTGAGCTCCCCACTGGTTTTGGCTGGGGACACCAGACCACGTTTCTTGGAGTACTCTACGTCTGAGTGTCATTTCTTCAATGGGACGGAGCGGGTGCGGTTCCTGGACAGATACTTCTATAACCAAGAGGAGTACGTGCGCTTCGACAGCGACGTGGGGGAGTTCCGGGCGGTGACGGAGCTGGGGCGGCCTGATGAGGAGTACTGGAACAGCCAGAAGGACTTCCTGGAAGACAGGCGGGCCGCGGTGGACACCTACTGCAGACACAACTACGGGGTTGTGGAGAGCTTCACAGTGCAGCGGCGAGTCCATCCTAAGGTGACTGTGTATCCTTCAAAGACCCAGCCCCTGCAGCACCACAACCTCCTGGTCTGTTCTGTGAGTGGTTTCTATCCAGGCAGCATTGAAGTCAGGTGGTTCCGGAATGGCCAGGAAGAGAAGACTGGGGTGGTGTCCACAGGCCTGATCCACAATGGAGACTGGACCTTCCAGACCCTGGTGATGCTGGAAACAGTTCCTCGGAGTGGAGAGGTTTACACCTGCCAAGTGGAGCACCCAAGCGTGACAAGCCCTCTCACAGTGGAATGGAGAGCACGGTCTGAATCTGCACAGAGCAAGATGCTGAGTGGAGTCGGGGGCTTTGTGCTGGGCCTGCTCTTCCTTGGGGCCGGGCTGTTCATCTACTTCAGGAATCAGAAAGGACACTCTGGACTTCAGCCAAGAGGATTCCTGAGCTGA
ORF Protein Sequence MVCLRLPGGSCMAVLTVTLMVLSSPLVLAGDTRPRFLEYSTSECHFFNGTERVRFLDRYFYNQEEYVRFDSDVGEFRAVTELGRPDEEYWNSQKDFLEDRRAAVDTYCRHNYGVVESFTVQRRVHPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSGLQPRGFLS

Reference




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    Associated products


    Category Cat No. Products Name
    Biosimilar GMP-Bios-INN-736 Pre-Made Apolizumab Biosimilar, Whole Mab, Anti-HLA-DRB/HLA-DRB1 Antibody: Anti-DRB1/SS1 therapeutic antibody
    Target Antibody GM-Tg-g-T83611-Ab Anti-DRB1/ HLA-DRB1/ HLA-DR1B monoclonal antibody
    Target Antigen GM-Tg-g-T83611-Ag HLA-DRB1 VLP (virus-like particle)
    ORF Viral Vector pGMAP000059 Human HLA-DRB1 Adenovirus plasmid
    ORF Viral Vector pGMAP000274 Human HLA-DRB1 Adenovirus plasmid
    ORF Viral Vector vGMAP000059 Human HLA-DRB1 Adenovirus particle
    ORF Viral Vector vGMAP000274 Human HLA-DRB1 Adenovirus particle


    Target information

    Target ID GM-T83611
    Target Name HLA-DRB1
    Gene Group Identifier
    （Target Gene ID in Homo species)         		3123
    Gene ID 3123 (Homo sapiens)
    Gene Symbols & Synonyms HLA-DRB1,SS1,DRB1,HLA-DRB,HLA-DR1B
    Target Alternative Names DRB1,DRB1 beta chain,HLA class II histocompatibility antigen,HLA-DR1B,HLA-DRB,HLA-DRB1,Human leukocyte antigen DRB1 (HLA-DRB1),SS1
    Uniprot Accession P01911
    Additional SwissProt Accessions: P01911
    Uniprot Entry Name
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target, INN Index
    Disease cancer
    Disease from KEGG Phagosome, Cell adhesion molecules, Antigen processing and presentation, Hematopoietic cell lineage, Th1 and Th2 cell differentiation, Th17 cell differentiation, Intestinal immune network for IgA production, Type I diabetes mellitus, Leishmaniasis, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Influenza A, Human T-cell leukemia virus 1 infection, Epstein-Barr virus infection, Asthma, Autoimmune thyroid disease, Inflammatory bowel disease, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Viral myocarditis
    Gene Ensembl ENSG00000196126
    Target Classification Tumor-associated antigen (TAA)


    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.