Human DHFR ORF/cDNA clone-Adenovirus plasmid (BC000192)

Cat. No.: pGMAP000102
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human DHFR/ adenoviral expression plasmid for DHFR adenovirus packaging, DHFR adenovirus.

Our GM-Adenovirus vector is optimized with the GMVC-modified Adeasy adenovirus packaging system. Find more about the GMVC-modified adenovirus packaging system.

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Product Description

Catalog ID pGMAP000102
Gene Name DHFR
Accession Number BC000192
Gene ID 1719
Species Human
Product Type Adenovirus plasmid (overexpression)
Insert Length 564 bp
Gene Alias
Fluorescent Reporter GFP
Mammalian Cell Selection Null
Fusion Tag 3xflag (C-Terminal)
Promoter EF1
Resistance Kanamycin
ORF Nucleotide Sequence ATGGTTGGTTCGCTAAACTGCATCGTCGCTGTGTCCCAGAACATGGGCATCGGCAAGAACGGGGACCTGCCCTGGCCACCGCTCAGGAATGAATTCAGATATTTCCAGAGAATGACCACAACCTCTTCAGTAGAAGGTAAACAGAATCTGGTGATTATGGGTAAGAAGACCTGGTTCTCCATTCCTGAGAAGAATCGACCTTTAAAGGGTAGAATTAATTTAGTTCTCAGCAGAGAACTCAAGGAACCTCCACAAGGAGCTCATTTTCTTTCCAGAAGTCTAGATGATGCCTTAAAACTTACTGAACAACCAGAATTAGCAAATAAAGTAGACATGGTCTGGATAGTTGGTGGCAGTTCTGTTTATAAGGAAGCCATGAATCACCCAGGCCATCTTAAACTATTTGTGACAAGGATCATGCAAGACTTTGAAAGTGACACGTTTTTTCCAGAAATTGATTTGGAGAAATATAAACTTCTGCCAGAATACCCAGGTGTTCTCTCTGATGTCCAGGAGGAGAAAGGCATTAAGTACAAATTTGAAGTATATGAGAAGAATGATTAA
ORF Protein Sequence MVGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFSIPEKNRPLKGRINLVLSRELKEPPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSSVYKEAMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKFEVYEKND

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T17345-Ab Anti-DHFR monoclonal antibody
    Target Antigen GM-Tg-g-T17345-Ag DHFR protein
    ORF Viral Vector pGMLP000510 Human DHFR Lentivirus plasmid
    ORF Viral Vector pGMAP000102 Human DHFR Adenovirus plasmid
    ORF Viral Vector vGMLP000510 Human DHFR Lentivirus particle
    ORF Viral Vector vGMAP000102 Human DHFR Adenovirus particle


    Target information

    Target ID GM-T17345
    Target Name DHFR
    Gene Group Identifier
    （Target Gene ID in Homo species)         		1719
    Gene ID 100073256 (Equus caballus), 101087964 (Felis catus), 13361 (Mus musculus), 1719 (Homo sapiens)
    24312 (Rattus norvegicus), 479165 (Canis lupus familiaris), 508809 (Bos taurus), 711268 (Macaca mulatta)
    Gene Symbols & Synonyms DHFR,Dhfr,8430436I03Rik,DYR,DHFR1,DHFRP1,Dhfr1
    Target Alternative Names 8430436I03Rik,DHFR,DHFR1,DHFRP1,DYR,Dhfr,Dhfr1,Dihydrofolate reductase
    Uniprot Accession P00374,P00375,P00376,Q920D2
    Additional SwissProt Accessions: P00375,P00374,Q920D2,P00376
    Uniprot Entry Name
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease cancer
    Disease from KEGG Metabolic pathways, Antifolate resistance
    Gene Ensembl ENSECAG00000026827, ENSMUSG00000021707, ENSG00000228716, ENSCAFG00845005830, ENSBTAG00000007681, ENSMMUG00000018283
    Target Classification Tumor-associated antigen (TAA)


    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.