Human DIO2/5DII/D2 ORF/cDNA clone-Adenovirus plasmid (NM_013989)

Cat. No.: pGMAD000267
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human DIO2/5DII/D2 adenoviral expression plasmid for DIO2 adenovirus packaging, DIO2 adenovirus.

Our GM-Adenovirus vector is optimized with the GMVC-modified Adeasy adenovirus packaging system. Find more about the GMVC-modified adenovirus packaging system.

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Product Description

Catalog ID pGMAD000267
Gene Name DIO2
Accession Number NM_013989
Gene ID 1734
Species Human
Product Type Adenovirus plasmid (overexpression)
Insert Length 822 bp
Gene Alias 5DII,D2,DIOII,SelY,TXDI2
Fluorescent Reporter Null
Mammalian Cell Selection Null
Fusion Tag Null
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGGCATCCTCAGCGTAGACTTGCTGATCACACTGCAAATTCTGCCAGTTTTTTTCTCCAACTGCCTCTTCCTGGCTCTCTATGACTCGGTCATTCTGCTCAAGCACGTGGTGCTGCTGTTGAGCCGCTCCAAGTCCACTCGCGGAGAGTGGCGGCGCATGCTGACCTCAGAGGGACTGCGCTGCGTCTGGAAGAGCTTCCTCCTCGATGCCTACAAACAGGTGAAATTGGGTGAGGATGCCCCCAATTCCAGTGTGGTGCATGTCTCCAGTACAGAAGGAGGTGACAACAGTGGCAATGGTACCCAGGAGAAGATAGCTGAGGGAGCCACATGCCACCTTCTTGACTTTGCCAGCCCTGAGCGCCCACTAGTGGTCAACTTTGGCTCAGCCACTTGACCTCCTTTCACGAGCCAGCTGCCAGCCTTCCGCAAACTGGTGGAAGAGTTCTCCTCAGTGGCTGACTTCCTGCTGGTCTACATTGATGAGGCTCATCCATCAGATGGCTGGGCGATACCGGGGGACTCCTCTTTGTCTTTTGAGGTGAAGAAGCACCAGAACCAGGAAGATCGATGTGCAGCAGCCCAGCAGCTTCTGGAGCGTTTCTCCTTGCCGCCCCAGTGCCGAGTTGTGGCTGACCGCATGGACAATAACGCCAACATAGCTTACGGGGTAGCCTTTGAACGTGTGTGCATTGTGCAGAGACAGAAAATTGCTTATCTGGGAGGAAAGGGCCCCTTCTCCTACAACCTTCAAGAAGTCCGGCATTGGCTGGAGAAGAATTTCAGCAAGAGATGAAAGAAAACTAGATTAGCTGGTTAA
ORF Protein Sequence MGILSVDLLITLQILPVFFSNCLFLALYDSVILLKHVVLLLSRSKSTRGEWRRMLTSEGLRCVWKSFLLDAYKQVKLGEDAPNSSVVHVSSTEGGDNSGNGTQEKIAEGATCHLLDFASPERPLVVNFGSATUPPFTSQLPAFRKLVEEFSSVADFLLVYIDEAHPSDGWAIPGDSSLSFEVKKHQNQEDRCAAAQQLLERFSLPPQCRVVADRMDNNANIAYGVAFERVCIVQRQKIAYLGGKGPFSYNLQEVRHWLEKNFSKRUKKTRLAG

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-MP0359-Ab Anti-IOD2/ DIO2/ 5DII monoclonal antibody
    Target Antigen GM-Tg-g-MP0359-Ag DIO2 VLP (virus-like particle)
    ORF Viral Vector pGMAD000267 Human DIO2 Adenovirus plasmid
    ORF Viral Vector vGMAD000267 Human DIO2 Adenovirus particle


    Target information

    Target ID GM-MP0359
    Target Name DIO2
    Gene Group Identifier
    （Target Gene ID in Homo species)         		1734
    Gene ID 100052547 (Equus caballus), 101088170 (Felis catus), 13371 (Mus musculus), 1734 (Homo sapiens)
    490813 (Canis lupus familiaris), 494548 (Bos taurus), 65162 (Rattus norvegicus), 707484 (Macaca mulatta)
    Gene Symbols & Synonyms DIO2,Dio2,5DII,DIOII,D2,SelY,TXDI2,SELENOY
    Target Alternative Names 5DII,D2,DIO2,DIOII,Dio2,SELENOY,SelY,TXDI2,Type 2 DI,Type II iodothyronine deiodinase,Type-II 5'-deiodinase
    Uniprot Accession P70551,Q5I3B2,Q92813,Q9Z1Y9
    Additional SwissProt Accessions: Q9Z1Y9,Q92813,Q5I3B2,P70551
    Uniprot Entry Name
    Protein Sub-location Transmembrane Protein
    Category
    Disease
    Disease from KEGG Thyroid hormone signaling pathway
    Gene Ensembl ENSECAG00000030788, ENSMUSG00000007682, ENSG00000211448, ENSBTAG00000064181
    Target Classification


    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.