Human PNPLA2/1110001C14Rik/ATGL ORF/cDNA clone-Adeno-associate virus(AAV) plasmid (NM_020376.4)

Cat. No.: pGMAAV001954
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human PNPLA2/1110001C14Rik/ATGL Adeno-associated virus expression plasmid (ITR-vector) for PNPLA2 AAV packaging, PNPLA2 AAV production.The purified Human PNPLA2/1110001C14Rik/ATGL AAV particle serves as an invaluable asset for in-depth in vivo PNPLA2 studies, mechanism of action (MOA) research, and the evolution of PNPLA2-associated gene therapy strategies.

Our GM-AAV ITR vector is optimized with the G-NEXT™ multi-serotypes AAV vector system. Explore the G-NEXT™ system in detail.

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Product Description

Catalog ID pGMAAV001954
Gene Name PNPLA2
Accession Number NM_020376.4
Gene ID 57104
Species Human
Product Type Adeno-associate virus(AAV) plasmid (overexpression)
Insert Length 1515 bp
Gene Alias 1110001C14Rik,ATGL,FP17548,iPLA2zeta,PEDF-R,TTS-2.2,TTS2
Fluorescent Reporter EGFP
Mammalian Cell Selection Null
Fusion Tag 3xflag (C-Terminal)
Promoter CTNT
Resistance Amplicin
ORF Nucleotide Sequence ATGTTTCCCCGCGAGAAGACGTGGAACATCTCGTTCGCGGGCTGCGGCTTCCTCGGCGTCTACTACGTCGGCGTGGCCTCCTGCCTCCGCGAGCACGCGCCCTTCCTGGTGGCCAACGCCACGCACATCTACGGCGCCTCGGCCGGGGCGCTCACGGCCACGGCGCTGGTCACCGGGGTCTGCCTGGGTGAGGCTGGTGCCAAGTTCATTGAGGTATCTAAAGAGGCCCGGAAGCGGTTCCTGGGCCCCCTGCACCCCTCCTTCAACCTGGTAAAGATCATCCGCAGTTTCCTGCTGAAGGTCCTGCCTGCTGATAGCCATGAGCATGCCAGTGGGCGCCTGGGCATCTCCCTGACCCGCGTGTCAGACGGCGAGAATGTCATTATATCCCACTTCAACTCCAAGGACGAGCTCATCCAGGCCAATGTCTGCAGCGGTTTCATCCCCGTGTACTGTGGGCTCATCCCTCCCTCCCTCCAGGGGGTGCGCTACGTGGATGGTGGCATTTCAGACAACCTGCCACTCTATGAGCTTAAGAACACCATCACAGTGTCCCCCTTCTCGGGCGAGAGTGACATCTGTCCGCAGGACAGCTCCACCAACATCCACGAGCTGCGGGTCACCAACACCAGCATCCAGTTCAACCTGCGCAACCTCTACCGCCTCTCCAAGGCCCTCTTCCCGCCGGAGCCCCTGGTGCTGCGAGAGATGTGCAAGCAGGGATACCGGGATGGCCTGCGCTTTCTGCAGCGGAACGGCCTCCTGAACCGGCCCAACCCCTTGCTGGCGTTGCCCCCCGCCCGCCCCCACGGCCCAGAGGACAAGGACCAGGCAGTGGAGAGCGCCCAAGCGGAGGATTACTCGCAGCTGCCCGGAGAAGATCACATCCTGGAGCACCTGCCCGCCCGGCTCAATGAGGCCCTGCTGGAGGCCTGCGTGGAGCCCACGGACCTGCTGACCACCCTCTCCAACATGCTGCCTGTGCGTCTGGCCACGGCCATGATGGTGCCCTACACGCTGCCGCTGGAGAGCGCTCTGTCCTTCACCATCCGCTTGCTGGAGTGGCTGCCCGACGTTCCCGAGGACATCCGGTGGATGAAGGAGCAGACGGGCAGCATCTGCCAGTACCTGGTGATGCGCGCCAAGAGGAAGCTGGGCAGGCACCTGCCCTCCAGGCTGCCGGAGCAGGTGGAGCTGCGCCGCGTCCAGTCGCTGCCGTCCGTGCCGCTGTCCTGCGCCGCCTACAGAGAGGCACTGCCCGGCTGGATGCGCAACAACCTCTCGCTGGGGGACGCGCTGGCCAAGTGGGAGGAGTGCCAGCGCCAGCTGCTGCTCGGCCTCTTCTGCACCAACGTGGCCTTCCCGCCCGAAGCTCTGCGCATGCGCGCACCCGCCGACCCGGCTCCCGCCCCCGCGGACCCAGCATCCCCGCAGCACCAGCTGGCCGGGCCTGCCCCCTTGCTGAGCACCCCTGCTCCCGAGGCCCGGCCCGTGATCGGGGCCCTGGGGCTGTGA
ORF Protein Sequence MFPREKTWNISFAGCGFLGVYYVGVASCLREHAPFLVANATHIYGASAGALTATALVTGVCLGEAGAKFIEVSKEARKRFLGPLHPSFNLVKIIRSFLLKVLPADSHEHASGRLGISLTRVSDGENVIISHFNSKDELIQANVCSGFIPVYCGLIPPSLQGVRYVDGGISDNLPLYELKNTITVSPFSGESDICPQDSSTNIHELRVTNTSIQFNLRNLYRLSKALFPPEPLVLREMCKQGYRDGLRFLQRNGLLNRPNPLLALPPARPHGPEDKDQAVESAQAEDYSQLPGEDHILEHLPARLNEALLEACVEPTDLLTTLSNMLPVRLATAMMVPYTLPLESALSFTIRLLEWLPDVPEDIRWMKEQTGSICQYLVMRAKRKLGRHLPSRLPEQVELRRVQSLPSVPLSCAAYREALPGWMRNNLSLGDALAKWEECQRQLLLGLFCTNVAFPPEALRMRAPADPAPAPADPASPQHQLAGPAPLLSTPAPEARPVIGALGL

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-MP1396-Ab Anti-PLPL2/ PNPLA2/ 1110001C14Rik monoclonal antibody
    Target Antigen GM-Tg-g-MP1396-Ag PNPLA2 VLP (virus-like particle)
    ORF Viral Vector pGMAAV001954 Human PNPLA2 Adeno-associate virus(AAV) plasmid
    ORF Viral Vector pGMPC001195 Human PNPLA2 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC001634 Human PNPLA2 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMAAV001954 Human PNPLA2 Adeno-associate virus(AAV) particle


    Target information

    Target ID GM-MP1396
    Target Name ATGL/PNPLA2
    Gene Group Identifier
    （Target Gene ID in Homo species)         		57104
    Gene ID 100146758 (Equus caballus), 101082263 (Felis catus), 361676 (Rattus norvegicus), 508493 (Bos taurus)
    57104 (Homo sapiens), 611403 (Canis lupus familiaris), 66853 (Mus musculus), 700824 (Macaca mulatta)
    Gene Symbols & Synonyms PNPLA2,Pnpla2,RGD1309044,ATGL,TTS2,PEDF-R,FP17548,TTS-2.2,iPLA2zeta,1110001C14Rik,Atgl,0610039C21Rik
    Target Alternative Names 0610039C21Rik,1110001C14Rik,ATGL,Adipose triglyceride lipase,Atgl,Calcium-independent phospholipase A2-zeta (iPLA2-zeta),Desnutrin,FP17548,PEDF-R,PNPLA2,Patatin-like phospholipase domain-containing protein 2,Pigment epithelium-derived factor receptor (PEDF-R),Pnpla2,RGD1309044,TTS-2.2,TTS2,TTS2.2,Transport-secretion protein 2 (TTS2),iPLA2zeta
    Uniprot Accession P0C548,Q2KI18,Q8BJ56,Q96AD5
    Additional SwissProt Accessions: P0C548,Q2KI18,Q96AD5,Q8BJ56
    Uniprot Entry Name
    Protein Sub-location Transmembrane Protein
    Category
    Disease
    Disease from KEGG Metabolic pathways, Regulation of lipolysis in adipocytes
    Gene Ensembl ENSBTAG00000005144, ENSG00000177666, ENSMUSG00000025509, ENSMMUG00000056078
    Target Classification


    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.