Human PFKFB3/iPFK-2/IPFK2 ORF/cDNA clone-Adeno-associate virus(AAV) plasmid (NM_004566.4)

Cat. No.: pGMAAV001756
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human PFKFB3/iPFK-2/IPFK2 Adeno-associated virus expression plasmid (ITR-vector) for PFKFB3 AAV packaging, PFKFB3 AAV production.The purified Human PFKFB3/iPFK-2/IPFK2 AAV particle serves as an invaluable asset for in-depth in vivo PFKFB3 studies, mechanism of action (MOA) research, and the evolution of PFKFB3-associated gene therapy strategies.

Our GM-AAV ITR vector is optimized with the G-NEXT™ multi-serotypes AAV vector system. Explore the G-NEXT™ system in detail.

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Product Description

Catalog ID pGMAAV001756
Gene Name PFKFB3
Accession Number NM_004566.4
Gene ID 5209
Species Human
Product Type Adeno-associate virus(AAV) plasmid (overexpression)
Insert Length 1563 bp
Gene Alias iPFK-2,IPFK2,PFK2
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Null
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGCCGTTGGAACTGACGCAGAGCCGAGTGCAGAAGATCTGGGTGCCCGTGGACCACAGGCCCTCGTTGCCCAGATCCTGTGGGCCAAAGCTGACCAACTCCCCCACCGTCATCGTCATGGTGGGCCTCCCCGCCCGGGGCAAGACCTACATCTCCAAGAAGCTGACTCGCTACCTCAACTGGATTGGCGTCCCCACAAAAGTGTTCAACGTCGGGGAGTATCGCCGGGAGGCTGTGAAGCAGTACAGCTCCTACAACTTCTTCCGCCCCGACAATGAGGAAGCCATGAAAGTCCGGAAGCAATGTGCCTTAGCTGCCTTGAGAGATGTCAAAAGCTACCTGGCGAAAGAAGGGGGACAAATTGCGGTTTTCGATGCCACCAATACTACTAGAGAGAGGAGACACATGATCCTTCATTTTGCCAAAGAAAATGACTTTAAGGCGTTTTTCATCGAGTCGGTGTGCGACGACCCTACAGTTGTGGCCTCCAATATCATGGAAGTTAAAATCTCCAGCCCGGATTACAAAGACTGCAACTCGGCAGAAGCCATGGACGACTTCATGAAGAGGATCAGTTGCTATGAAGCCAGCTACCAGCCCCTCGACCCCGACAAATGCGACAGGGACTTGTCGCTGATCAAGGTGATTGACGTGGGCCGGAGGTTCCTGGTGAACCGGGTGCAGGACCACATCCAGAGCCGCATCGTGTACTACCTGATGAACATCCACGTGCAGCCGCGTACCATCTACCTGTGCCGGCACGGCGAGAACGAGCACAACCTCCAGGGCCGCATCGGGGGCGACTCAGGCCTGTCCAGCCGGGGCAAGAAGTTTGCCAGTGCTCTGAGCAAGTTCGTGGAGGAGCAGAACCTGAAGGACCTGCGCGTGTGGACCAGCCAGCTGAAGAGCACCATCCAGACGGCCGAGGCGCTGCGGCTGCCCTACGAGCAGTGGAAGGCGCTCAATGAGATCGACGCGGGCGTCTGTGAGGAGCTGACCTACGAGGAGATCAGGGACACCTACCCTGAGGAGTATGCGCTGCGGGAGCAGGACAAGTACTATTACCGCTACCCCACCGGGGAGTCCTACCAGGACCTGGTCCAGCGCTTGGAGCCAGTGATCATGGAGCTGGAGCGGCAGGAGAATGTGCTGGTCATCTGCCACCAGGCCGTCCTGCGCTGCCTGCTTGCCTACTTCCTGGATAAGAGTGCAGAGGAGATGCCCTACCTGAAATGCCCTCTTCACACCGTCCTGAAACTGACGCCTGTCGCTTATGGCTGCCGTGTGGAATCCATCTACCTGAACGTGGAGTCCGTCTGCACACACCGGGAGAGGTCAGAGGATGCAAAGAAGGGACCTAACCCGCTCATGAGACGCAATAGTGTCACCCCGCTAGCCAGCCCCGAACCCACCAAAAAGCCTCGCATCAACAGCTTTGAGGAGCATGTGGCCTCCACCTCGGCCGCCCTGCCCAGCTGCCTGCCCCCGGAGGTGCCCACGCAGCTGCCTGGACAAAACATGAAAGGCTCCCGGAGCAGCGCTGACTCCTCCAGGAAACACTGA
ORF Protein Sequence MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLNWIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQIAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNSAEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLMNIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQLKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTGESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKLTPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFEEHVASTSAALPSCLPPEVPTQLPGQNMKGSRSSADSSRKH

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T23787-Ab Anti-PFKFB3 monoclonal antibody
    Target Antigen GM-Tg-g-T23787-Ag PFKFB3 protein
    ORF Viral Vector pGMLP000744 Human PFKFB3 Lentivirus plasmid
    ORF Viral Vector pGMLP005289 Human PFKFB3 Lentivirus plasmid
    ORF Viral Vector pGMAAV001756 Human PFKFB3 Adeno-associate virus(AAV) plasmid
    ORF Viral Vector vGMLP000744 Human PFKFB3 Lentivirus particle
    ORF Viral Vector vGMLP005289 Human PFKFB3 Lentivirus particle
    ORF Viral Vector vGMAAV001756 Human PFKFB3 Adeno-associate virus(AAV) particle


    Target information

    Target ID GM-T23787
    Target Name PFKFB3
    Gene Group Identifier
    （Target Gene ID in Homo species)         		5209
    Gene ID 100070251 (Equus caballus), 101100062 (Felis catus), 117276 (Rattus norvegicus), 170768 (Mus musculus)
    407183 (Bos taurus), 487139 (Canis lupus familiaris), 5209 (Homo sapiens), 713062 (Macaca mulatta)
    Gene Symbols & Synonyms PFKFB3,Pfkfb3,iPFK-2,uPFK-2,E330010H22Rik,PFK2,IPFK2
    Target Alternative Names 6-P2ase 3,6-P2ase brain/placenta-type isozyme,6-bisphosphatase 3,6-phosphofructo-2-kinase/fructose-2,6PF-2-K/Fru-2,E330010H22Rik,IPFK2,PFK/FBPase 3,PFK2,PFKFB3,Pfkfb3,Renal carcinoma antigen NY-REN-56,iPFK-2,uPFK-2
    Uniprot Accession O35552,Q16875,Q28901
    Additional SwissProt Accessions: O35552,Q28901,Q16875
    Uniprot Entry Name
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease
    Disease from KEGG Metabolic pathways, HIF-1 signaling pathway
    Gene Ensembl ENSECAG00000012172, ENSMUSG00000026773, ENSBTAG00000008401, ENSCAFG00845001712, ENSG00000170525, ENSMMUG00000010596
    Target Classification


    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.