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Human RDH12/LCA13/RP53 ORF/cDNA clone-Adeno-associate virus(AAV) plasmid (NM_152443.2)
Cat. No.: pGMAAV001533
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days
Pre-made Human RDH12/LCA13/RP53 Adeno-associated virus expression plasmid (ITR-vector) for RDH12 AAV packaging, RDH12 AAV production.The purified Human RDH12/LCA13/RP53 AAV particle serves as an invaluable asset for in-depth in vivo RDH12 studies, mechanism of action (MOA) research, and the evolution of RDH12-associated gene therapy strategies.
Our GM-AAV ITR vector is optimized with the G-NEXT™ multi-serotypes AAV vector system. Explore the G-NEXT™ system in detail.
Datasheet
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Product Description
| Catalog ID | pGMAAV001533 |
| Gene Name | RDH12 |
| Accession Number | NM_152443.2 |
| Gene ID | 145226 |
| Species | Human |
| Product Type | Adeno-associate virus(AAV) plasmid (overexpression) |
| Insert Length | 951 bp |
| Gene Alias | LCA13,RP53,SDR7C2 |
| Fluorescent Reporter | ZsGreen |
| Mammalian Cell Selection | Null |
| Fusion Tag | 1xflag (C-Terminal) |
| Promoter | CMV |
| Resistance | Amplicin |
| ORF Nucleotide Sequence | ATGCTGGTCACCTTGGGACTGCTCACCTCCTTCTTCTCGTTCCTGTATATGGTAGCTCCATCCATCAGGAAGTTCTTTGCTGGTGGAGTGTGTAGAACAAATGTGCAGCTTCCTGGCAAGGTAGTGGTGATCACTGGCGCCAACACGGGCATTGGCAAGGAGACGGCCAGAGAGCTCGCTAGCCGAGGAGCCCGAGTCTATATTGCCTGCAGAGATGTACTGAAGGGGGAGTCTGCTGCCAGTGAAATCCGAGTGGATACAAAGAACTCCCAGGTGCTGGTGCGGAAATTGGACCTATCCGACACCAAATCTATCCGAGCCTTTGCTGAGGGCTTTCTGGCAGAGGAAAAGCAGCTCCATATTCTGATCAACAATGCGGGAGTAATGATGTGTCCATATTCCAAGACAGCTGATGGCTTTGAAACCCACCTGGGAGTCAACCACCTGGGCCACTTCCTCCTCACCTACCTGCTCCTGGAGCGGCTAAAGGTGTCTGCCCCTGCACGGGTGGTTAATGTGTCCTCGGTGGCTCACCACATTGGCAAGATTCCCTTCCACGACCTCCAGAGCGAGAAGCGCTACAGCAGGGGTTTTGCCTATTGCCACAGCAAGCTGGCCAATGTGCTTTTTACTCGTGAGCTGGCCAAGAGGCTCCAAGGCACCGGGGTCACCACCTACGCAGTGCACCCAGGCGTCGTCCGCTCTGAGCTGGTCCGGCACTCCTCCCTGCTCTGCCTGCTCTGGCGGCTCTTCTCCCCCTTTGTCAAGACGGCACGGGAGGGGGCGCAGACCAGCCTGCACTGCGCCCTGGCTGAGGGCCTGGAGCCCCTGAGTGGCAAGTACTTCAGTGACTGCAAGAGGACCTGGGTGTCTCCAAGGGCCCGAAATAACAAAACAGCTGAGCGCCTATGGAATGTCAGCTGTGAGCTTCTAGGAATCCGGTGGGAGTAG |
| ORF Protein Sequence | MLVTLGLLTSFFSFLYMVAPSIRKFFAGGVCRTNVQLPGKVVVITGANTGIGKETARELASRGARVYIACRDVLKGESAASEIRVDTKNSQVLVRKLDLSDTKSIRAFAEGFLAEEKQLHILINNAGVMMCPYSKTADGFETHLGVNHLGHFLLTYLLLERLKVSAPARVVNVSSVAHHIGKIPFHDLQSEKRYSRGFAYCHSKLANVLFTRELAKRLQGTGVTTYAVHPGVVRSELVRHSSLLCLLWRLFSPFVKTAREGAQTSLHCALAEGLEPLSGKYFSDCKRTWVSPRARNNKTAERLWNVSCELLGIRWE |
Reference
Data / case study
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Associated products
| Category | Cat No. | Products Name |
|---|---|---|
| Target Antibody | GM-Tg-g-SE1513-Ab | Anti-RDH12/ LCA13/ RP53 functional antibody |
| Target Antigen | GM-Tg-g-SE1513-Ag | RDH12 protein |
| ORF Viral Vector | pGMLP003533 | Human RDH12 Lentivirus plasmid |
| ORF Viral Vector | pGMLP003880 | Human RDH12 Lentivirus plasmid |
| ORF Viral Vector | pGMAAV001533 | Human RDH12 Adeno-associate virus(AAV) plasmid |
| ORF Viral Vector | pGMAAV001534 | Human RDH12 Adeno-associate virus(AAV) plasmid |
| ORF Viral Vector | vGMLP003533 | Human RDH12 Lentivirus particle |
| ORF Viral Vector | vGMLP003880 | Human RDH12 Lentivirus particle |
| ORF Viral Vector | vGMAAV001533 | Human RDH12 Adeno-associate virus(AAV) particle |
| ORF Viral Vector | vGMAAV001534 | Human RDH12 Adeno-associate virus(AAV) particle |
Target information
| Target ID | GM-SE1513 |
| Target Name | RDH12 |
|
Gene Group Identifier （Target Gene ID in Homo species) |
145226 |
| Gene ID |
100063369 (Equus caballus), 101093615 (Felis catus), 145226 (Homo sapiens), 314264 (Rattus norvegicus) 369021 (Bos taurus), 490744 (Canis lupus familiaris), 711438 (Macaca mulatta), 77974 (Mus musculus) |
| Gene Symbols & Synonyms | RDH12,Rdh12,RP53,LCA13,SDR7C2,DSSDR2 |
| Target Alternative Names | All-trans and 9-cis retinol dehydrogenase,DSSDR2,LCA13,RDH12,RP53,Rdh12,Retinol dehydrogenase 12,SDR7C2,Short chain dehydrogenase/reductase family 7C member 2 |
| Uniprot Accession |
P59837,Q8BYK4,Q96NR8
Additional SwissProt Accessions: Q96NR8,P59837,Q8BYK4 |
| Uniprot Entry Name | |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | |
| Disease from KEGG | Metabolic pathways, Retinol metabolism |
| Gene Ensembl | ENSECAG00000015001, ENSG00000139988, ENSBTAG00000012838, ENSCAFG00845003571, ENSMMUG00000015869, ENSMUSG00000021123 |
| Target Classification |
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.