Human CXCR6/BONZO/CD186 ORF/cDNA clone-Adeno-associate virus(AAV) plasmid (NM_006564.2)

Cat. No.: pGMAAV000925
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human CXCR6/BONZO/CD186 Adeno-associated virus expression plasmid (ITR-vector) for CXCR6 AAV packaging, CXCR6 AAV production.The purified Human CXCR6/BONZO/CD186 AAV particle serves as an invaluable asset for in-depth in vivo CXCR6 studies, mechanism of action (MOA) research, and the evolution of CXCR6-associated gene therapy strategies.

Our GM-AAV ITR vector is optimized with the G-NEXT™ multi-serotypes AAV vector system. Explore the G-NEXT™ system in detail.

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Product Description

Catalog ID pGMAAV000925
Gene Name CXCR6
Accession Number NM_006564.2
Gene ID 10663
Species Human
Product Type Adeno-associate virus(AAV) plasmid (overexpression)
Insert Length 1029 bp
Gene Alias BONZO,CD186,CDw186,STRL33,TYMSTR
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Null
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGCAGAGCATGATTACCATGAAGACTATGGGTTCAGCAGTTTCAATGACAGCAGCCAGGAGGAGCATCAAGACTTCCTGCAGTTCAGCAAGGTCTTTCTGCCCTGCATGTACCTGGTGGTGTTTGTCTGTGGTCTGGTGGGGAACTCTCTGGTGCTGGTCATATCCATCTTCTACCATAAGTTGCAGAGCCTGACGGATGTGTTCCTGGTGAACCTACCCCTGGCTGACCTGGTGTTTGTCTGCACTCTGCCCTTCTGGGCCTATGCAGGCATCCATGAATGGGTGTTTGGCCAGGTCATGTGCAAGAGCCTACTGGGCATCTACACTATTAACTTCTACACGTCCATGCTCATCCTCACCTGCATCACTGTGGATCGTTTCATTGTAGTGGTTAAGGCCACCAAGGCCTACAACCAGCAAGCCAAGAGGATGACCTGGGGCAAGGTCACCAGCTTGCTCATCTGGGTGATATCCCTGCTGGTTTCCTTGCCCCAAATTATCTATGGCAATGTCTTTAATCTCGACAAGCTCATATGTGGTTACCATGACGAGGCAATTTCCACTGTGGTTCTTGCCACCCAGATGACACTGGGGTTCTTCTTGCCACTGCTCACCATGATTGTCTGCTATTCAGTCATAATCAAAACACTGCTTCATGCTGGAGGCTTCCAGAAGCACAGATCTCTAAAGATCATCTTCCTGGTGATGGCTGTGTTCCTGCTGACCCAGATGCCCTTCAACCTCATGAAGTTCATCCGCAGCACACACTGGGAATACTATGCCATGACCAGCTTTCACTACACCATCATGGTGACAGAGGCCATCGCATACCTGAGGGCCTGCCTTAACCCTGTGCTCTATGCCTTTGTCAGCCTGAAGTTTCGAAAGAACTTCTGGAAACTTGTGAAGGACATTGGTTGCCTCCCTTACCTTGGGGTCTCACATCAATGGAAATCTTCTGAGGACAATTCCAAGACTTTTTCTGCCTCCCACAATGTGGAGGCCACCAGCATGTTCCAGTTATAG
ORF Protein Sequence MAEHDYHEDYGFSSFNDSSQEEHQDFLQFSKVFLPCMYLVVFVCGLVGNSLVLVISIFYHKLQSLTDVFLVNLPLADLVFVCTLPFWAYAGIHEWVFGQVMCKSLLGIYTINFYTSMLILTCITVDRFIVVVKATKAYNQQAKRMTWGKVTSLLIWVISLLVSLPQIIYGNVFNLDKLICGYHDEAISTVVLATQMTLGFFLPLLTMIVCYSVIIKTLLHAGGFQKHRSLKIIFLVMAVFLLTQMPFNLMKFIRSTHWEYYAMTSFHYTIMVTEAIAYLRACLNPVLYAFVSLKFRKNFWKLVKDIGCLPYLGVSHQWKSSEDNSKTFSASHNVEATSMFQL

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T53975-Ab Anti-CXCR6/ BONZO/ CD186 monoclonal antibody
    Target Antigen GM-Tg-g-T53975-Ag CXCR6 VLP (virus-like particle)
    Cytokine cks-Tg-g-GM-T53975 chemokine (C-X-C motif) receptor 6 (CXCR6) protein & antibody
    ORF Viral Vector pGMLP002468 Human CXCR6 Lentivirus plasmid
    ORF Viral Vector pGMAAV000925 Human CXCR6 Adeno-associate virus(AAV) plasmid
    ORF Viral Vector vGMLP002468 Human CXCR6 Lentivirus particle
    ORF Viral Vector vGMAAV000925 Human CXCR6 Adeno-associate virus(AAV) particle


    Target information

    Target ID GM-T53975
    Target Name CXCR6/CD186
    Gene Group Identifier
    （Target Gene ID in Homo species)         		10663
    Gene ID 100124593 (Rattus norvegicus), 100630558 (Equus caballus), 101083494 (Felis catus), 10663 (Homo sapiens)
    506807 (Bos taurus), 608840 (Canis lupus familiaris), 713829 (Macaca mulatta), 80901 (Mus musculus)
    Gene Symbols & Synonyms Cxcr6,CXCR6,BONZO,CD186,CDw186,STRL33,TYMSTR,Bonzo
    Target Alternative Names CXCR6, CD186,C-X-C chemokine receptor type 6,CXC-R6, CXCR-6,CDw186, G-protein coupled receptor STRL33, G-protein coupled receptor bonzo,BONZO,CD186,CDw186,STRL33,TYMSTR
    Uniprot Accession O00574,Q9EQ16,Q9XT45
    Additional SwissProt Accessions: O00574,Q9XT45,Q9EQ16
    Uniprot Entry Name
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target, Cytokine Target
    Disease
    Disease from KEGG Cytokine-cytokine receptor interaction, Chemokine signaling pathway
    Gene Ensembl ENSECAG00000003105, ENSG00000172215, ENSBTAG00000015708, ENSCAFG00845012275, ENSMMUG00000023587, ENSMUSG00000048521
    Target Classification GPCR


    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.