Human WT1/AWT1/GUD ORF/cDNA clone-Adeno-associate virus(AAV) plasmid (NM_001198551.1)

Cat. No.: pGMAAV000871
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human WT1/AWT1/GUD Adeno-associated virus expression plasmid (ITR-vector) for WT1 AAV packaging, WT1 AAV production.The purified Human WT1/AWT1/GUD AAV particle serves as an invaluable asset for in-depth in vivo WT1 studies, mechanism of action (MOA) research, and the evolution of WT1-associated gene therapy strategies.

Our GM-AAV ITR vector is optimized with the G-NEXT™ multi-serotypes AAV vector system. Explore the G-NEXT™ system in detail.

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Product Description

Catalog ID pGMAAV000871
Gene Name WT1
Accession Number NM_001198551.1
Gene ID 7490
Species Human
Product Type Adeno-associate virus(AAV) plasmid (overexpression)
Insert Length 909 bp
Gene Alias AWT1,GUD,NPHS4,WAGR,WIT-2,WT33
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Null
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGAGAAGGGTTACAGCACGGTCACCTTCGACGGGACGCCCAGCTACGGTCACACGCCCTCGCACCATGCGGCGCAGTTCCCCAACCACTCATTCAAGCATGAGGATCCCATGGGCCAGCAGGGCTCGCTGGGTGAGCAGCAGTACTCGGTGCCGCCCCCGGTCTATGGCTGCCACACCCCCACCGACAGCTGCACCGGCAGCCAGGCTTTGCTGCTGAGGACGCCCTACAGCAGTGACAATTTATACCAAATGACATCCCAGCTTGAATGCATGACCTGGAATCAGATGAACTTAGGAGCCACCTTAAAGGGAGTTGCTGCTGGGAGCTCCAGCTCAGTGAAATGGACAGAAGGGCAGAGCAACCACAGCACAGGGTACGAGAGCGATAACCACACAACGCCCATCCTCTGCGGAGCCCAATACAGAATACACACGCACGGTGTCTTCAGAGGCATTCAGGATGTGCGACGTGTGCCTGGAGTAGCCCCGACTCTTGTACGGTCGGCATCTGAGACCAGTGAGAAACGCCCCTTCATGTGTGCTTACCCAGGCTGCAATAAGAGATATTTTAAGCTGTCCCACTTACAGATGCACAGCAGGAAGCACACTGGTGAGAAACCATACCAGTGTGACTTCAAGGACTGTGAACGAAGGTTTTCTCGTTCAGACCAGCTCAAAAGACACCAAAGGAGACATACAGGTGTGAAACCATTCCAGTGTAAAACTTGTCAGCGAAAGTTCTCCCGGTCCGACCACCTGAAGACCCACACCAGGACTCATACAGGTGAAAAGCCCTTCAGCTGTCGGTGGCCAAGTTGTCAGAAAAAGTTTGCCCGGTCAGATGAATTAGTCCGCCATCACAACATGCATCAGAGAAACATGACCAAACTCCAGCTGGCGCTTTGA
ORF Protein Sequence MEKGYSTVTFDGTPSYGHTPSHHAAQFPNHSFKHEDPMGQQGSLGEQQYSVPPPVYGCHTPTDSCTGSQALLLRTPYSSDNLYQMTSQLECMTWNQMNLGATLKGVAAGSSSSVKWTEGQSNHSTGYESDNHTTPILCGAQYRIHTHGVFRGIQDVRRVPGVAPTLVRSASETSEKRPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQRNMTKLQLAL

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T29960-Ab Anti-WT1 monoclonal antibody
    Target Antigen GM-Tg-g-T29960-Ag WT1 protein
    ORF Viral Vector pGMLV000621 Human wt1 Lentivirus plasmid
    ORF Viral Vector pGMAAV000871 Human WT1 Adeno-associate virus(AAV) plasmid
    ORF Viral Vector vGMLV000621 Human wt1 Lentivirus particle
    ORF Viral Vector vGMAAV000871 Human WT1 Adeno-associate virus(AAV) particle


    Target information

    Target ID GM-T29960
    Target Name WT1
    Gene Group Identifier
    （Target Gene ID in Homo species)         		7490
    Gene ID 100072704 (Equus caballus), 101088518 (Felis catus), 22431 (Mus musculus), 24883 (Rattus norvegicus)
    609253 (Canis lupus familiaris), 696061 (Macaca mulatta), 7490 (Homo sapiens), 782183 (Bos taurus)
    Gene Symbols & Synonyms WT1,Wt1,Wt-1,D630046I19Rik,GUD,AWT1,WAGR,WT-1,WT33,NPHS4,WIT-2,WT
    Target Alternative Names AWT1,D630046I19Rik,GUD,NPHS4,WAGR,WIT-2,WT,WT-1,WT1,WT33,Wilms tumor protein,Wt-1,Wt1
    Uniprot Accession P19544,P22561,P49952
    Additional SwissProt Accessions: P22561,P49952,P19544
    Uniprot Entry Name
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target, Immuno-oncology Target
    Disease cancer
    Disease from KEGG
    Gene Ensembl ENSECAG00000022308, ENSMUSG00000016458, ENSCAFG00845027359, ENSMMUG00000009881, ENSG00000184937
    Target Classification Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA)


    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.