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Human VEGFA/MVCD1/VEGF ORF/cDNA clone-Adeno-associate virus(AAV) plasmid (NM_001171626.1)
Cat. No.: pGMAAV000786
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days
Pre-made Human VEGFA/MVCD1/VEGF Adeno-associated virus expression plasmid (ITR-vector) for VEGFA AAV packaging, VEGFA AAV production.The purified Human VEGFA/MVCD1/VEGF AAV particle serves as an invaluable asset for in-depth in vivo VEGFA studies, mechanism of action (MOA) research, and the evolution of VEGFA-associated gene therapy strategies.
Our GM-AAV ITR vector is optimized with the G-NEXT™ multi-serotypes AAV vector system. Explore the G-NEXT™ system in detail.
Datasheet
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Product Description
| Catalog ID | pGMAAV000786 |
| Gene Name | VEGFA |
| Accession Number | NM_001171626.1 |
| Gene ID | 7422 |
| Species | Human |
| Product Type | Adeno-associate virus(AAV) plasmid (overexpression) |
| Insert Length | 576 bp |
| Gene Alias | MVCD1,VEGF,VPF |
| Fluorescent Reporter | ZsGreen |
| Mammalian Cell Selection | Null |
| Fusion Tag | 3xflag (C-Terminal) |
| Promoter | CMV |
| Resistance | Amplicin |
| ORF Nucleotide Sequence | ATGAACTTTCTGCTGTCTTGGGTGCATTGGAGCCTTGCCTTGCTGCTCTACCTCCACCATGCCAAGTGGTCCCAGGCTGCACCCATGGCAGAAGGAGGAGGGCAGAATCATCACGAAGTGGTGAAGTTCATGGATGTCTATCAGCGCAGCTACTGCCATCCAATCGAGACCCTGGTGGACATCTTCCAGGAGTACCCTGATGAGATCGAGTACATCTTCAAGCCATCCTGTGTGCCCCTGATGCGATGCGGGGGCTGCTGCAATGACGAGGGCCTGGAGTGTGTGCCCACTGAGGAGTCCAACATCACCATGCAGATTATGCGGATCAAACCTCACCAAGGCCAGCACATAGGAGAGATGAGCTTCCTACAGCACAACAAATGTGAATGCAGACCAAAGAAAGATAGAGCAAGACAAGAAAATCCCTGTGGGCCTTGCTCAGAGCGGAGAAAGCATTTGTTTGTACAAGATCCGCAGACGTGTAAATGTTCCTGCAAAAACACAGACTCGCGTTGCAAGGCGAGGCAGCTTGAGTTAAACGAACGTACTTGCAGATGTGACAAGCCGAGGCGGTGA |
| ORF Protein Sequence | MNFLLSWVHWSLALLLYLHHAKWSQAAPMAEGGGQNHHEVVKFMDVYQRSYCHPIETLVDIFQEYPDEIEYIFKPSCVPLMRCGGCCNDEGLECVPTEESNITMQIMRIKPHQGQHIGEMSFLQHNKCECRPKKDRARQENPCGPCSERRKHLFVQDPQTCKCSCKNTDSRCKARQLELNERTCRCDKPRR |
Reference
Data / case study
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Associated products
Target information
| Target ID | GM-T20761 |
| Target Name | VEGFA |
|
Gene Group Identifier （Target Gene ID in Homo species) |
7422 |
| Gene ID |
100033839 (Equus caballus), 22339 (Mus musculus), 281572 (Bos taurus), 403802 (Canis lupus familiaris) 493845 (Felis catus), 574209 (Macaca mulatta), 7422 (Homo sapiens), 83785 (Rattus norvegicus) |
| Gene Symbols & Synonyms | VEGFA,Vegfa,VPF,Vpf,Vegf,L-VEGF,VEGF,VEGF-A,eVEGF120,eVEGF164,MVCD1,VEGF111,VEGF164 |
| Target Alternative Names | L-VEGF,MVCD1,VEGF,VEGF-A,VEGF111,VEGF164,VEGFA,VPF,Vascular endothelial growth factor A,Vascular permeability factor (VPF),Vegf,Vegfa,Vpf,eVEGF120,eVEGF164,long form |
| Uniprot Accession |
P15691,P15692,P16612,Q00731,Q9GKR0,Q9MYV3
Additional SwissProt Accessions: Q9GKR0,Q00731,P15691,Q9MYV3,P15692,P16612 |
| Uniprot Entry Name | |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Therapeutics Target, Diagnostics Biomarker, Immuno-oncology Target, INN Index, Cytokine Target |
| Disease | cancer, Lung Cancer, Malignant neoplasm of prostate, Chronic Kidney Disease, Malignant neoplasm of bladder, Type 2 diabetes mellitus with diabetic nephropathy, Urinary bladder urothelial carcinoma |
| Disease from KEGG | EGFR tyrosine kinase inhibitor resistance, MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, HIF-1 signaling pathway, PI3K-Akt signaling pathway, Focal adhesion, Relaxin signaling pathway, AGE-RAGE signaling pathway in diabetic complications, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Proteoglycans in cancer, Chemical carcinogenesis - receptor activation, Renal cell carcinoma, Pancreatic cancer, Bladder cancer, Rheumatoid arthritis, Fluid shear stress and atherosclerosis |
| Gene Ensembl | ENSECAG00000009402, ENSMUSG00000023951, ENSMMUG00000004577, ENSG00000112715 |
| Target Classification | Checkpoint-Immuno Oncology |
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