Human IL4/BCGF-1/BCGF1 ORF/cDNA clone-Adeno-associate virus(AAV) plasmid (NM_000589)

Cat. No.: pGMAAV000365
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human IL4/BCGF-1/BCGF1 Adeno-associated virus expression plasmid (ITR-vector) for IL4 AAV packaging, IL4 AAV production.The purified Human IL4/BCGF-1/BCGF1 AAV particle serves as an invaluable asset for in-depth in vivo IL4 studies, mechanism of action (MOA) research, and the evolution of IL4-associated gene therapy strategies.

Our GM-AAV ITR vector is optimized with the G-NEXT™ multi-serotypes AAV vector system. Explore the G-NEXT™ system in detail.

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Product Description

Catalog ID pGMAAV000365
Gene Name IL4
Accession Number NM_000589
Gene ID 3565
Species Human
Product Type Adeno-associate virus(AAV) plasmid (overexpression)
Insert Length 462 bp
Gene Alias BCGF-1,BCGF1,BSF-1,BSF1,IL-4
Fluorescent Reporter GFP
Mammalian Cell Selection Null
Fusion Tag Null
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGGTCTCACCTCCCAACTGCTTCCCCCTCTGTTCTTCCTGCTAGCATGTGCCGGCAACTTTGTCCACGGACACAAGTGCGATATCACCTTACAGGAGATCATCAAAACTTTGAACAGCCTCACAGAGCAGAAGACTCTGTGCACCGAGTTGACCGTAACAGACATCTTTGCTGCCTCCAAGAACACAACTGAGAAGGAAACCTTCTGCAGGGCTGCGACTGTGCTCCGGCAGTTCTACAGCCACCATGAGAAGGACACTCGCTGCCTGGGTGCGACTGCACAGCAGTTCCACAGGCACAAGCAGCTGATCCGATTCCTGAAACGGCTCGACAGGAACCTCTGGGGCCTGGCGGGCTTGAATTCCTGTCCTGTGAAGGAAGCCAACCAGAGTACGTTGGAAAACTTCTTGGAAAGGCTAAAGACGATCATGAGAGAGAAATATTCAAAGTGTTCGAGCTGA
ORF Protein Sequence MGLTSQLLPPLFFLLACAGNFVHGHKCDITLQEIIKTLNSLTEQKTLCTELTVTDIFAASKNTTEKETFCRAATVLRQFYSHHEKDTRCLGATAQQFHRHKQLIRFLKRLDRNLWGLAGLNSCPVKEANQSTLENFLERLKTIMREKYSKCSS

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Biosimilar GMP-Bios-INN-945 Pre-Made Pascolizumab Biosimilar, Whole Mab, Anti-Il4 Antibody: Anti-BCGF-1/BCGF1/BSF-1/BSF1/IL-4 therapeutic antibody
    Biosimilar GMP-Bios-ab-492 Pre-Made Romilkimab biosimilar, Bispecific Dual Variable Domain IG, Anti-IL13;IL4 Antibody: Anti-IL-13/P600;BCGF-1/BCGF1/BSF-1/BSF1/IL-4 therapeutic antibody
    Target Antibody GM-Tg-g-T00239-Ab Anti-IL4/ BCGF-1/ BCGF1 functional antibody
    Target Antigen GM-Tg-g-T00239-Ag IL4 protein
    ORF Viral Vector pGMLP004452 Human IL4 Lentivirus plasmid
    ORF Viral Vector pGMAAV000365 Human IL4 Adeno-associate virus(AAV) plasmid
    ORF Viral Vector pGMLP-IL-007 Human IL4 Lentivirus plasmid
    ORF Viral Vector pGMAP-IL-090 Human IL4 Adenovirus plasmid
    ORF Viral Vector pGMPC000614 Human IL4 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP004452 Human IL4 Lentivirus particle
    ORF Viral Vector vGMAAV000365 Human IL4 Adeno-associate virus(AAV) particle
    ORF Viral Vector vGMLP-IL-007 Human IL4 Lentivirus particle
    ORF Viral Vector vGMAP-IL-090 Human IL4 Adenovirus particle


    Target information

    Target ID GM-T00239
    Target Name IL-4/IL4
    Gene Group Identifier
    （Target Gene ID in Homo species)         		3565
    Gene ID 100034225 (Equus caballus), 16189 (Mus musculus), 280824 (Bos taurus), 287287 (Rattus norvegicus)
    3565 (Homo sapiens), 403785 (Canis lupus familiaris), 574281 (Macaca mulatta), 751514 (Felis catus)
    Gene Symbols & Synonyms IL4,Il4,IL-4,BSF-1,Il-4,Il4e12,BSF1,BCGF1,BCGF-1
    Target Alternative Names B-cell stimulatory factor 1 (BSF-1),BCGF-1,BCGF1,BSF-1,BSF1,Binetrakin,IL-4,IL4,Il-4,Il4,Il4e12,Interleukin-4,Lymphocyte stimulatory factor 1,Pitrakinra
    Uniprot Accession O77762,P05112,P07750,P20096,P30367,P42202,P51492,P55030
    Additional SwissProt Accessions: P42202,P07750,P30367,P20096,P05112,O77762,P51492,P55030
    Uniprot Entry Name
    Protein Sub-location Secreted Protein/Potential Cytokines
    Category Therapeutics Target, INN Index
    Disease cancer, Breast Cancer
    Disease from KEGG Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, IL-17 signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Fc epsilon RI signaling pathway, Intestinal immune network for IgA production, Leishmaniasis, Pathways in cancer, Asthma, Autoimmune thyroid disease, Inflammatory bowel disease, Allograft rejection
    Gene Ensembl ENSECAG00000008299, ENSMUSG00000000869, ENSBTAG00000015957, ENSG00000113520, ENSCAFG00845010991, ENSMMUG00000003133
    Target Classification


    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.