Human CSF2/CSF/GMCSF ORF/cDNA clone-Adeno-associate virus(AAV) plasmid (NM_000758.3)

Cat. No.: pGMAAV000364
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human CSF2/CSF/GMCSF Adeno-associated virus expression plasmid (ITR-vector) for CSF2 AAV packaging, CSF2 AAV production.The purified Human CSF2/CSF/GMCSF AAV particle serves as an invaluable asset for in-depth in vivo CSF2 studies, mechanism of action (MOA) research, and the evolution of CSF2-associated gene therapy strategies.

Our GM-AAV ITR vector is optimized with the G-NEXT™ multi-serotypes AAV vector system. Explore the G-NEXT™ system in detail.

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Product Description

Catalog ID pGMAAV000364
Gene Name CSF2
Accession Number NM_000758.3
Gene ID 1437
Species Human
Product Type Adeno-associate virus(AAV) plasmid (overexpression)
Insert Length 435 bp
Gene Alias CSF,GMCSF
Fluorescent Reporter GFP
Mammalian Cell Selection Null
Fusion Tag Null
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGTGGCTGCAGAGCCTGCTGCTCTTGGGCACTGTGGCCTGCAGCATCTCTGCACCCGCCCGCTCGCCCAGCCCCAGCACGCAGCCCTGGGAGCATGTGAATGCCATCCAGGAGGCCCGGCGTCTCCTGAACCTGAGTAGAGACACTGCTGCTGAGATGAATGAAACAGTAGAAGTCATCTCAGAAATGTTTGACCTCCAGGAGCCGACCTGCCTACAGACCCGCCTGGAGCTGTACAAGCAGGGCCTGCGGGGCAGCCTCACCAAGCTCAAGGGCCCCTTGACCATGATGGCCAGCCACTACAAGCAGCACTGCCCTCCAACCCCGGAAACTTCCTGTGCAACCCAGATTATCACCTTTGAAAGTTTCAAAGAGAACCTGAAGGACTTTCTGCTTGTCATCCCCTTTGACTGCTGGGAGCCAGTCCAGGAGTGA
ORF Protein Sequence MWLQSLLLLGTVACSISAPARSPSPSTQPWEHVNAIQEARRLLNLSRDTAAEMNETVEVISEMFDLQEPTCLQTRLELYKQGLRGSLTKLKGPLTMMASHYKQHCPPTPETSCATQIITFESFKENLKDFLLVIPFDCWEPVQE

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Biosimilar GMP-Bios-ab-303 Pre-Made Lenzilumab biosimilar, Whole mAb, Anti-CSF2 Antibody: Anti-CSF/GMCSF therapeutic antibody
    Biosimilar GMP-Bios-ab-244 Pre-Made Gimsilumab biosimilar, Whole mAb, Anti-CSF2 Antibody: Anti-CSF/GMCSF therapeutic antibody
    Biosimilar GMP-Bios-ab-453 Pre-Made Plonmarlimab biosimilar, Whole mAb, Anti-CSF2 Antibody: Anti-CSF/GMCSF therapeutic antibody
    Biosimilar GMP-Bios-ab-362 Pre-Made Namilumab biosimilar, Whole mAb, Anti-CSF2 Antibody: Anti-CSF/GMCSF therapeutic antibody
    Biosimilar GMP-Bios-ab-415 Pre-Made Otilimab biosimilar, Whole mAb, Anti-CSF2 Antibody: Anti-CSF/GMCSF therapeutic antibody
    Target Antibody GM-Tg-g-T74002-Ab Anti-CSF2/ CSF/ GMCSF monoclonal antibody
    Target Antigen GM-Tg-g-T74002-Ag CSF2 VLP (virus-like particle)
    ORF Viral Vector pGMLP000211 Human CSF2 Lentivirus plasmid
    ORF Viral Vector pGMAAV000364 Human CSF2 Adeno-associate virus(AAV) plasmid
    ORF Viral Vector pGMPC004740 Human CSF2 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP000211 Human CSF2 Lentivirus particle
    ORF Viral Vector vGMAAV000364 Human CSF2 Adeno-associate virus(AAV) particle


    Target information

    Target ID GM-T74002
    Target Name GM-CSF/CSF2
    Gene Group Identifier
    （Target Gene ID in Homo species)         		1437
    Gene ID 100033981 (Equus caballus), 101094153 (Felis catus), 116630 (Rattus norvegicus), 12981 (Mus musculus)
    1437 (Homo sapiens), 281095 (Bos taurus), 403923 (Canis lupus familiaris), 574371 (Macaca mulatta)
    Gene Symbols & Synonyms CSF2,Csf2,GM-CSF,Gmcsf,Gm-csf,CSF,Csfgm,GMCSF,Gm-CSf,MGI-IGM
    Target Alternative Names CSF,CSF2,Colony-stimulating factor (CSF),Csf2,Csfgm,GM-CSF,GMCSF,Gm-CSf,Gm-csf,Gmcsf,Granulocyte-macrophage colony-stimulating factor,MGI-IGM,Molgramostin,Sargramostim
    Uniprot Accession P01587,P04141,P11052,P48749,P48750
    Additional SwissProt Accessions: P48750,P01587,P04141,P11052,P48749
    Uniprot Entry Name
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target, Immuno-oncology Target, INN Index
    Disease metastatic tumors, Overactive bladder
    Disease from KEGG Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, Hematopoietic cell lineage, Natural killer cell mediated cytotoxicity, IL-17 signaling pathway, T cell receptor signaling pathway, Fc epsilon RI signaling pathway, TNF signaling pathway, Amoebiasis, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Acute myeloid leukemia, Rheumatoid arthritis
    Gene Ensembl ENSECAG00000009678, ENSMUSG00000018916, ENSG00000164400, ENSBTAG00000001570, ENSCAFG00845009774, ENSMMUG00000016915
    Target Classification Pathway, Checkpoint-Immuno Oncology


    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.