Human YAP1/COB1/YAP ORF/cDNA clone-Adeno-associate virus(AAV) plasmid (NM_001130145)

Cat. No.: pGMAAV000314
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human YAP1/COB1/YAP Adeno-associated virus expression plasmid (ITR-vector) for YAP1 AAV packaging, YAP1 AAV production.The purified Human YAP1/COB1/YAP AAV particle serves as an invaluable asset for in-depth in vivo YAP1 studies, mechanism of action (MOA) research, and the evolution of YAP1-associated gene therapy strategies.

Our GM-AAV ITR vector is optimized with the G-NEXT™ multi-serotypes AAV vector system. Explore the G-NEXT™ system in detail.

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Product Description

Catalog ID pGMAAV000314
Gene Name YAP1
Accession Number NM_001130145
Gene ID 10413
Species Human
Product Type Adeno-associate virus(AAV) plasmid (overexpression)
Insert Length 1515 bp
Gene Alias COB1,YAP,YAP2,YAP65,YKI
Fluorescent Reporter GFP
Mammalian Cell Selection Null
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGATCCCGGGCAGCAGCCGCCGCCTCAACCGGCCCCCCAGGGCCAAGGGCAGCCGCCTTCGCAGCCCCCGCAGGGGCAGGGCCCGCCGTCCGGACCCGGGCAACCGGCACCCGCGGCGACCCAGGCGGCGCCGCAGGCACCCCCCGCCGGGCATCAGATCGTGCACGTCCGCGGGGACTCGGAGACCGACCTGGAGGCGCTCTTCAACGCCGTCATGAACCCCAAGACGGCCAACGTGCCCCAGACCGTGCCCATGAGGCTCCGGAAGCTGCCCGACTCCTTCTTCAAGCCGCCGGAGCCCAAATCCCACTCCCGACAGGCCAGTACTGATGCAGGCACTGCAGGAGCCCTGACTCCACAGCATGTTCGAGCTCATTCCTCTCCAGCTTCTCTGCAGTTGGGAGCTGTTTCTCCTGGGACACTGACCCCCACTGGAGTAGTCTCTGGCCCAGCAGCTACACCCACAGCTCAGCATCTTCGACAGTCTTCTTTTGAGATACCTGATGATGTACCTCTGCCAGCAGGTTGGGAGATGGCAAAGACATCTTCTGGTCAGAGATACTTCTTAAATCACATCGATCAGACAACAACATGGCAGGACCCCAGGAAGGCCATGCTGTCCCAGATGAACGTCACAGCCCCCACCAGTCCACCAGTGCAGCAGAATATGATGAACTCGGCTTCAGGTCCTCTTCCTGATGGATGGGAACAAGCCATGACTCAGGATGGAGAAATTTACTATATAAACCATAAGAACAAGACCACCTCTTGGCTAGACCCAAGGCTTGACCCTCGTTTTGCCATGAACCAGAGAATCAGTCAGAGTGCTCCAGTGAAACAGCCACCACCCCTGGCTCCCCAGAGCCCACAGGGAGGCGTCATGGGTGGCAGCAACTCCAACCAGCAGCAACAGATGCGACTGCAGCAACTGCAGATGGAGAAGGAGAGGCTGCGGCTGAAACAGCAAGAACTGCTTCGGCAGGCAATGCGGAATATCAATCCCAGCACAGCAAATTCTCCAAAATGTCAGGAGTTAGCCCTGCGTAGCCAGTTACCAACACTGGAGCAGGATGGTGGGACTCAAAATCCAGTGTCTTCTCCCGGGATGTCTCAGGAATTGAGAACAATGACGACCAATAGCTCAGATCCTTTCCTTAACAGTGGCACCTATCACTCTCGAGATGAGAGTACAGACAGTGGACTAAGCATGAGCAGCTACAGTGTCCCTCGAACCCCAGATGACTTCCTGAACAGTGTGGATGAGATGGATACAGGTGATACTATCAACCAAAGCACCCTGCCCTCACAGCAGAACCGTTTCCCAGACTACCTTGAAGCCATTCCTGGGACAAATGTGGACCTTGGAACACTGGAAGGAGATGGAATGAACATAGAAGGAGAGGAGCTGATGCCAAGTCTGCAGGAAGCTTTGAGTTCTGACATCCTTAATGACATGGAGTCTGTTTTGGCTGCCACCAAGCTAGATAAAGAAAGCTTTCTTACATGGTTATAG
ORF Protein Sequence MDPGQQPPPQPAPQGQGQPPSQPPQGQGPPSGPGQPAPAATQAAPQAPPAGHQIVHVRGDSETDLEALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPPEPKSHSRQASTDAGTAGALTPQHVRAHSSPASLQLGAVSPGTLTPTGVVSGPAATPTAQHLRQSSFEIPDDVPLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPRKAMLSQMNVTAPTSPPVQQNMMNSASGPLPDGWEQAMTQDGEIYYINHKNKTTSWLDPRLDPRFAMNQRISQSAPVKQPPPLAPQSPQGGVMGGSNSNQQQQMRLQQLQMEKERLRLKQQELLRQAMRNINPSTANSPKCQELALRSQLPTLEQDGGTQNPVSSPGMSQELRTMTTNSSDPFLNSGTYHSRDESTDSGLSMSSYSVPRTPDDFLNSVDEMDTGDTINQSTLPSQQNRFPDYLEAIPGTNVDLGTLEGDGMNIEGEELMPSLQEALSSDILNDMESVLAATKLDKESFLTWL

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T94048-Ab Anti-YAP1 monoclonal antibody
    Target Antigen GM-Tg-g-T94048-Ag YAP1 protein
    ORF Viral Vector pGMLP005732 Human YAP1 Lentivirus plasmid
    ORF Viral Vector pGMLV000392 Human YAP1 Lentivirus plasmid
    ORF Viral Vector pGMLV000567 Human YAP1 Lentivirus plasmid
    ORF Viral Vector pGMLV000777 Human YAP1 Lentivirus plasmid
    ORF Viral Vector pGMLV000998 Human YAP1 Lentivirus plasmid
    ORF Viral Vector pGMLV001167 Human YAP1 Lentivirus plasmid
    ORF Viral Vector pGMLV001168 Human YAP1 Lentivirus plasmid
    ORF Viral Vector pGMLV001285 Human YAP1 Lentivirus plasmid
    ORF Viral Vector pGMLV002267 Human YAP1 Lentivirus plasmid
    ORF Viral Vector pGMLV002426 Human YAP1 Lentivirus plasmid
    ORF Viral Vector pGMAD000063 Human YAP1 Adenovirus plasmid
    ORF Viral Vector pGMAD000620 Human YAP1 Adenovirus plasmid
    ORF Viral Vector pGMAAV000314 Human YAP1 Adeno-associate virus(AAV) plasmid
    ORF Viral Vector pGMAAV000884 Human YAP1 Adeno-associate virus(AAV) plasmid
    ORF Viral Vector pGMLP-SPh-021 Human YAP1 Lentivirus plasmid
    ORF Viral Vector pGMAP-SPh-161 Human YAP1 Adenovirus plasmid
    ORF Viral Vector pGMPC000428 Human YAP1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC000964 Human YAP1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC001203 Human YAP1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC001272 Human YAP1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC001403 Human YAP1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC004851 Human YAP1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC004884 Human YAP1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP005732 Human YAP1 Lentivirus particle
    ORF Viral Vector vGMLV000392 Human YAP1 Lentivirus particle
    ORF Viral Vector vGMLV000567 Human YAP1 Lentivirus particle
    ORF Viral Vector vGMLV000777 Human YAP1 Lentivirus particle
    ORF Viral Vector vGMLV000998 Human YAP1 Lentivirus particle
    ORF Viral Vector vGMLV001167 Human YAP1 Lentivirus particle
    ORF Viral Vector vGMLV001168 Human YAP1 Lentivirus particle
    ORF Viral Vector vGMLV001285 Human YAP1 Lentivirus particle
    ORF Viral Vector vGMLV002267 Human YAP1 Lentivirus particle
    ORF Viral Vector vGMLV002426 Human YAP1 Lentivirus particle
    ORF Viral Vector vGMAD000063 Human YAP1 Adenovirus particle
    ORF Viral Vector vGMAD000620 Human YAP1 Adenovirus particle
    ORF Viral Vector vGMAAV000314 Human YAP1 Adeno-associate virus(AAV) particle
    ORF Viral Vector vGMAAV000884 Human YAP1 Adeno-associate virus(AAV) particle
    ORF Viral Vector vGMLP-SPh-021 Human YAP1 Lentivirus particle
    ORF Viral Vector vGMAP-SPh-161 Human YAP1 Adenovirus particle


    Target information

    Target ID GM-T94048
    Target Name YAP1
    Gene Group Identifier
    （Target Gene ID in Homo species)         		10413
    Gene ID 100068834 (Equus caballus), 100336629 (Bos taurus), 101101408 (Felis catus), 10413 (Homo sapiens)
    22601 (Mus musculus), 363014 (Rattus norvegicus), 479465 (Canis lupus familiaris), 704382 (Macaca mulatta)
    Gene Symbols & Synonyms YAP1,Yap1,YAP-65,YAP,YKI,COB1,YAP2,YAP-1,YAP65,Yap,Yki,Yap65,Yorkie
    Target Alternative Names COB1,Protein yorkie homolog,Transcriptional coactivator YAP1,YAP,YAP-1,YAP-65,YAP1,YAP2,YAP65,YKI,Yap,Yap1,Yap65,Yes-associated protein 1,Yes-associated protein YAP65 homolog,Yki,Yorkie
    Uniprot Accession P46937,P46938,Q2EJA0
    Additional SwissProt Accessions: P46937,P46938,Q2EJA0
    Uniprot Entry Name
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease cancer
    Disease from KEGG Hippo signaling pathway
    Gene Ensembl ENSECAG00000008660, ENSBTAG00000039307, ENSG00000137693, ENSMUSG00000053110, ENSCAFG00845001157, ENSMMUG00000003396
    Target Classification Tumor-associated antigen (TAA)


    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.