Human ADORA2A/A2aR/ADORA2 ORF/cDNA clone-Adeno-associate virus(AAV) plasmid (NM_001278497)

Cat. No.: pGMAAV000313
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human ADORA2A/A2aR/ADORA2 Adeno-associated virus expression plasmid (ITR-vector) for ADORA2A AAV packaging, ADORA2A AAV production.The purified Human ADORA2A/A2aR/ADORA2 AAV particle serves as an invaluable asset for in-depth in vivo ADORA2A studies, mechanism of action (MOA) research, and the evolution of ADORA2A-associated gene therapy strategies.

Our GM-AAV ITR vector is optimized with the G-NEXT™ multi-serotypes AAV vector system. Explore the G-NEXT™ system in detail.

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Product Description

Catalog ID pGMAAV000313
Gene Name ADORA2A
Accession Number NM_001278497
Gene ID 135
Species Human
Product Type Adeno-associate virus(AAV) plasmid (overexpression)
Insert Length 1239 bp
Gene Alias A2aR,ADORA2,RDC8
Fluorescent Reporter GFP
Mammalian Cell Selection Null
Fusion Tag 3xflag (C-Terminal)
Promoter CaMKⅡ
Resistance Amplicin
ORF Nucleotide Sequence ATGCCCATCATGGGCTCCTCGGTGTACATCACGGTGGAGCTGGCCATTGCTGTGCTGGCCATCCTGGGCAATGTGCTGGTGTGCTGGGCCGTGTGGCTCAACAGCAACCTGCAGAACGTCACCAACTACTTTGTGGTGTCACTGGCGGCGGCCGACATCGCAGTGGGTGTGCTCGCCATCCCCTTTGCCATCACCATCAGCACCGGGTTCTGCGCTGCCTGCCACGGCTGCCTCTTCATTGCCTGCTTCGTCCTGGTCCTCACGCAGAGCTCCATCTTCAGTCTCCTGGCCATCGCCATTGACCGCTACATTGCCATCCGCATCCCGCTCCGGTACAATGGCTTGGTGACCGGCACGAGGGCTAAGGGCATCATTGCCATCTGCTGGGTGCTGTCGTTTGCCATCGGCCTGACTCCCATGCTAGGTTGGAACAACTGCGGTCAGCCAAAGGAGGGCAAGAACCACTCCCAGGGCTGCGGGGAGGGCCAAGTGGCCTGTCTCTTTGAGGATGTGGTCCCCATGAACTACATGGTGTACTTCAACTTCTTTGCCTGTGTGCTGGTGCCCCTGCTGCTCATGCTGGGTGTCTATTTGCGGATCTTCCTGGCGGCGCGACGACAGCTGAAGCAGATGGAGAGCCAGCCTCTGCCGGGGGAGCGGGCACGGTCCACACTGCAGAAGGAGGTCCATGCTGCCAAGTCACTGGCCATCATTGTGGGGCTCTTTGCCCTCTGCTGGCTGCCCCTACACATCATCAACTGCTTCACTTTCTTCTGCCCCGACTGCAGCCACGCCCCTCTCTGGCTCATGTACCTGGCCATCGTCCTCTCCCACACCAATTCGGTTGTGAATCCCTTCATCTACGCCTACCGTATCCGCGAGTTCCGCCAGACCTTCCGCAAGATCATTCGCAGCCACGTCCTGAGGCAGCAAGAACCTTTCAAGGCAGCTGGCACCAGTGCCCGGGTCTTGGCAGCTCATGGCAGTGACGGAGAGCAGGTCAGCCTCCGTCTCAACGGCCACCCGCCAGGAGTGTGGGCCAACGGCAGTGCTCCCCACCCTGAGCGGAGGCCCAATGGCTATGCCCTGGGGCTGGTGAGTGGAGGGAGTGCCCAAGAGTCCCAGGGGAACACGGGCCTCCCAGACGTGGAGCTCCTTAGCCATGAGCTCAAGGGAGTGTGCCCAGAGCCCCCTGGCCTAGATGACCCCCTGGCCCAGGATGGAGCAGGAGTGTCCTGA
ORF Protein Sequence MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T77365-Ab Anti-AA2AR/ ADORA2A/ A2aR monoclonal antibody
    Target Antigen GM-Tg-g-T77365-Ag ADORA2A VLP (virus-like particle)
    ORF Viral Vector pGMAAV000023 Human ADORA2A Adeno-associate virus(AAV) plasmid
    ORF Viral Vector pGMAAV000313 Human ADORA2A Adeno-associate virus(AAV) plasmid
    ORF Viral Vector pGMAAV001052 Human ADORA2A Adeno-associate virus(AAV) plasmid
    ORF Viral Vector pGMAP000328 Human ADORA2A Adenovirus plasmid
    ORF Viral Vector vGMAAV000023 Human ADORA2A Adeno-associate virus(AAV) particle
    ORF Viral Vector vGMAAV000313 Human ADORA2A Adeno-associate virus(AAV) particle
    ORF Viral Vector vGMAAV001052 Human ADORA2A Adeno-associate virus(AAV) particle
    ORF Viral Vector vGMAP000328 Human ADORA2A Adenovirus particle


    Target information

    Target ID GM-T77365
    Target Name ADORA2A
    Gene Group Identifier
    （Target Gene ID in Homo species)         		135
    Gene ID 100034039 (Equus caballus), 101080742 (Felis catus), 11540 (Mus musculus), 135 (Homo sapiens)
    25369 (Rattus norvegicus), 403960 (Canis lupus familiaris), 617828 (Bos taurus), 707865 (Macaca mulatta)
    Gene Symbols & Synonyms ADORA2A,Adora2a,A2aR,A2AAR,AA2AR,ARA2A,RDC8,ADORA2,A2ar,ADENO,Adora2l1
    Target Alternative Names A2AAR,A2aR,A2ar,AA2AR,ADENO,ADORA2,ADORA2A,ARA2A,Adenosine receptor A2a,Adora2a,Adora2l1,RDC8
    Uniprot Accession P11617,P29274,P30543,Q60613,Q6TLI7
    Additional SwissProt Accessions: Q6TLI7,Q60613,P29274,P30543,P11617
    Uniprot Entry Name
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target, Immuno-oncology Target
    Disease
    Disease from KEGG Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction
    Gene Ensembl ENSECAG00000034739, ENSMUSG00000020178, ENSG00000128271, ENSCAFG00845022393, ENSBTAG00000016944, ENSMMUG00000008516
    Target Classification GPCR, Checkpoint-Immuno Oncology


    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.