Recombinant multi-species POLD1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine POLD1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes the 125-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 6. [provided by RefSeq, Mar 2012]
The Alternative Names of target: POLD1,DNA polymerase delta catalytic subunit,3'-5' exodeoxyribonuclease, DNA polymerase subunit delta p125,CDC2,MDPL,POLD,CRCS10,IMD120

Target products collectionGo to POLD1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-TA188-Ab-1/ GM-Tg-hg-TA188-Ab-2 Human POLD1 protein Human
GM-Tg-rg-TA188-Ab-1/ GM-Tg-rg-TA188-Ab-2 Rat POLD1 protein Rat
GM-Tg-mg-TA188-Ab-1/ GM-Tg-mg-TA188-Ab-2 Mouse POLD1 protein Mouse
GM-Tg-cynog-TA188-Ab-1/ GM-Tg-cynog-TA188-Ab-2 Cynomolgus/Rhesus macaque POLD1 monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-TA188-Ab-1/ GM-Tg-felg-TA188-Ab-2 Feline POLD1 protein Feline
GM-Tg-cang-TA188-Ab-1/ GM-Tg-cang-TA188-Ab-2 Canine POLD1 protein Canine
GM-Tg-bovg-TA188-Ab-1/ GM-Tg-bovg-TA188-Ab-2 Bovine POLD1 protein Bovine
GM-Tg-equg-TA188-Ab-1/ GM-Tg-equg-TA188-Ab-2 Equine POLD1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-TA188-Ab-1/ GM-Tg-hg-TA188-Ab-2; GM-Tg-rg-TA188-Ab-1/ GM-Tg-rg-TA188-Ab-2;
GM-Tg-mg-TA188-Ab-1/ GM-Tg-mg-TA188-Ab-2; GM-Tg-cynog-TA188-Ab-1/ GM-Tg-cynog-TA188-Ab-2;
GM-Tg-felg-TA188-Ab-1/ GM-Tg-felg-TA188-Ab-2; GM-Tg-cang-TA188-Ab-1/ GM-Tg-cang-TA188-Ab-2;
GM-Tg-bovg-TA188-Ab-1/ GM-Tg-bovg-TA188-Ab-2; GM-Tg-equg-TA188-Ab-1/ GM-Tg-equg-TA188-Ab-2
Products Name POLD1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name POLD1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine POLD1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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