Recombinant multi-species INHBE protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine INHBE protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate an inhibin beta subunit. Inhibins have been implicated in regulating numerous cellular processes including cell proliferation, apoptosis, immune response and hormone secretion. This gene may be upregulated under conditions of endoplasmic reticulum stress, and this protein may inhibit cellular proliferation and growth in pancreas and liver. [provided by RefSeq, Sep 2016]
The Alternative Names of target: Activin beta-E chain,INHBE,Inhbe,Inhibin beta E chain

Target products collectionGo to INHBE products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-TA172-Ag-1/ GM-Tg-hg-TA172-Ag-2 Human INHBE protein Human
GM-Tg-rg-TA172-Ag-1/ GM-Tg-rg-TA172-Ag-2 Rat INHBE protein Rat
GM-Tg-mg-TA172-Ag-1/ GM-Tg-mg-TA172-Ag-2 Mouse INHBE protein Mouse
GM-Tg-cynog-TA172-Ag-1/ GM-Tg-cynog-TA172-Ag-2 Cynomolgus/Rhesus macaque INHBE protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-TA172-Ag-1/ GM-Tg-felg-TA172-Ag-2 Feline INHBE protein Feline
GM-Tg-cang-TA172-Ag-1/ GM-Tg-cang-TA172-Ag-2 Canine INHBE protein Canine
GM-Tg-bovg-TA172-Ag-1/ GM-Tg-bovg-TA172-Ag-2 Bovine INHBE protein Bovine
GM-Tg-equg-TA172-Ag-1/ GM-Tg-equg-TA172-Ag-2 Equine INHBE protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-TA172-Ag-1/ GM-Tg-hg-TA172-Ag-2; GM-Tg-rg-TA172-Ag-1/ GM-Tg-rg-TA172-Ag-2;
GM-Tg-mg-TA172-Ag-1/ GM-Tg-mg-TA172-Ag-2; GM-Tg-cynog-TA172-Ag-1/ GM-Tg-cynog-TA172-Ag-2;
GM-Tg-felg-TA172-Ag-1/ GM-Tg-felg-TA172-Ag-2; GM-Tg-cang-TA172-Ag-1/ GM-Tg-cang-TA172-Ag-2;
GM-Tg-bovg-TA172-Ag-1/ GM-Tg-bovg-TA172-Ag-2; GM-Tg-equg-TA172-Ag-1/ GM-Tg-equg-TA172-Ag-2
Products Name INHBE protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name INHBE
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine INHBE protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.