Recombinant multi-species LDHB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LDHB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13. [provided by RefSeq, Feb 2016]
The Alternative Names of target: H-Ldh,HEL-S-281,L-lactate dehydrogenase B chain,LDH heart subunit (LDH-H),LDH-B,LDH-H,LDHB,LDHBD,Ldh-2,Ldh2,Ldhb,Renal carcinoma antigen NY-REN-46,TRG-5

Target products collectionGo to LDHB products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-TA076-Ag-1/ GM-Tg-hg-TA076-Ag-2 Human LDHB protein Human
GM-Tg-rg-TA076-Ag-1/ GM-Tg-rg-TA076-Ag-2 Rat LDHB protein Rat
GM-Tg-mg-TA076-Ag-1/ GM-Tg-mg-TA076-Ag-2 Mouse LDHB protein Mouse
GM-Tg-cynog-TA076-Ag-1/ GM-Tg-cynog-TA076-Ag-2 Cynomolgus/Rhesus macaque LDHB protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-TA076-Ag-1/ GM-Tg-felg-TA076-Ag-2 Feline LDHB protein Feline
GM-Tg-cang-TA076-Ag-1/ GM-Tg-cang-TA076-Ag-2 Canine LDHB protein Canine
GM-Tg-bovg-TA076-Ag-1/ GM-Tg-bovg-TA076-Ag-2 Bovine LDHB protein Bovine
GM-Tg-equg-TA076-Ag-1/ GM-Tg-equg-TA076-Ag-2 Equine LDHB protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-TA076-Ag-1/ GM-Tg-hg-TA076-Ag-2; GM-Tg-rg-TA076-Ag-1/ GM-Tg-rg-TA076-Ag-2;
GM-Tg-mg-TA076-Ag-1/ GM-Tg-mg-TA076-Ag-2; GM-Tg-cynog-TA076-Ag-1/ GM-Tg-cynog-TA076-Ag-2;
GM-Tg-felg-TA076-Ag-1/ GM-Tg-felg-TA076-Ag-2; GM-Tg-cang-TA076-Ag-1/ GM-Tg-cang-TA076-Ag-2;
GM-Tg-bovg-TA076-Ag-1/ GM-Tg-bovg-TA076-Ag-2; GM-Tg-equg-TA076-Ag-1/ GM-Tg-equg-TA076-Ag-2
Products Name LDHB protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name LDHB
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LDHB protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.