Recombinant multi-species CKMT2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CKMT2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
The Alternative Names of target: CKMT2,Creatine kinase S-type, mitochondrial,Basic-type mitochondrial creatine kinase (Mib-CK), Sarcomeric mitochondrial creatine kinase (S-MtCK),SMTCK

Target products collectionGo to CKMT2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-TA069-Ab-1/ GM-Tg-hg-TA069-Ab-2 Human CKMT2 protein Human
GM-Tg-rg-TA069-Ab-1/ GM-Tg-rg-TA069-Ab-2 Rat CKMT2 protein Rat
GM-Tg-mg-TA069-Ab-1/ GM-Tg-mg-TA069-Ab-2 Mouse CKMT2 protein Mouse
GM-Tg-cynog-TA069-Ab-1/ GM-Tg-cynog-TA069-Ab-2 Cynomolgus/Rhesus macaque CKMT2 monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-TA069-Ab-1/ GM-Tg-felg-TA069-Ab-2 Feline CKMT2 protein Feline
GM-Tg-cang-TA069-Ab-1/ GM-Tg-cang-TA069-Ab-2 Canine CKMT2 protein Canine
GM-Tg-bovg-TA069-Ab-1/ GM-Tg-bovg-TA069-Ab-2 Bovine CKMT2 protein Bovine
GM-Tg-equg-TA069-Ab-1/ GM-Tg-equg-TA069-Ab-2 Equine CKMT2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-TA069-Ab-1/ GM-Tg-hg-TA069-Ab-2; GM-Tg-rg-TA069-Ab-1/ GM-Tg-rg-TA069-Ab-2;
GM-Tg-mg-TA069-Ab-1/ GM-Tg-mg-TA069-Ab-2; GM-Tg-cynog-TA069-Ab-1/ GM-Tg-cynog-TA069-Ab-2;
GM-Tg-felg-TA069-Ab-1/ GM-Tg-felg-TA069-Ab-2; GM-Tg-cang-TA069-Ab-1/ GM-Tg-cang-TA069-Ab-2;
GM-Tg-bovg-TA069-Ab-1/ GM-Tg-bovg-TA069-Ab-2; GM-Tg-equg-TA069-Ab-1/ GM-Tg-equg-TA069-Ab-2
Products Name CKMT2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CKMT2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CKMT2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.