Recombinant multi-species AMPD1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine AMPD1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Adenosine monophosphate deaminase 1 catalyzes the deamination of AMP to IMP in skeletal muscle and plays an important role in the purine nucleotide cycle. Two other genes have been identified, AMPD2 and AMPD3, for the liver- and erythocyte-specific isoforms, respectively. Deficiency of the muscle-specific enzyme is apparently a common cause of exercise-induced myopathy and probably the most common cause of metabolic myopathy in the human. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010]
The Alternative Names of target: AMPD1,AMP deaminase 1,AMP deaminase isoform M, Myoadenylate deaminase,MAD,MADA,MMDD

Target products collectionGo to AMPD1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-TA002-Ab-1/ GM-Tg-hg-TA002-Ab-2 Human AMPD1 protein Human
GM-Tg-rg-TA002-Ab-1/ GM-Tg-rg-TA002-Ab-2 Rat AMPD1 protein Rat
GM-Tg-mg-TA002-Ab-1/ GM-Tg-mg-TA002-Ab-2 Mouse AMPD1 protein Mouse
GM-Tg-cynog-TA002-Ab-1/ GM-Tg-cynog-TA002-Ab-2 Cynomolgus/Rhesus macaque AMPD1 monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-TA002-Ab-1/ GM-Tg-felg-TA002-Ab-2 Feline AMPD1 protein Feline
GM-Tg-cang-TA002-Ab-1/ GM-Tg-cang-TA002-Ab-2 Canine AMPD1 protein Canine
GM-Tg-bovg-TA002-Ab-1/ GM-Tg-bovg-TA002-Ab-2 Bovine AMPD1 protein Bovine
GM-Tg-equg-TA002-Ab-1/ GM-Tg-equg-TA002-Ab-2 Equine AMPD1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-TA002-Ab-1/ GM-Tg-hg-TA002-Ab-2; GM-Tg-rg-TA002-Ab-1/ GM-Tg-rg-TA002-Ab-2;
GM-Tg-mg-TA002-Ab-1/ GM-Tg-mg-TA002-Ab-2; GM-Tg-cynog-TA002-Ab-1/ GM-Tg-cynog-TA002-Ab-2;
GM-Tg-felg-TA002-Ab-1/ GM-Tg-felg-TA002-Ab-2; GM-Tg-cang-TA002-Ab-1/ GM-Tg-cang-TA002-Ab-2;
GM-Tg-bovg-TA002-Ab-1/ GM-Tg-bovg-TA002-Ab-2; GM-Tg-equg-TA002-Ab-1/ GM-Tg-equg-TA002-Ab-2
Products Name AMPD1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name AMPD1
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine AMPD1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.