Recombinant multi-species ALDH1A1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ALDH1A1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet. [provided by RefSeq, Mar 2011]
The Alternative Names of target: 3-deoxyglucosone dehydrogenase,ALDC,ALDH-E1,ALDH1,ALDH11,ALDH1A1,ALHDII,Ahd2,Aldehyde dehydrogenase,Aldehyde dehydrogenase 1A1,Aldehyde dehydrogenase family 1 member A1,Aldh1,Aldh1a1,Aldh2,HEL-9,HEL-S-53e,HEL12,PUMB1,RALDH1,RalDH1,RalDH1),Retinal dehydrogenase 1 (RALDH 1,cytosolic
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-TA001-Ag-1/ GM-Tg-hg-TA001-Ag-2 | Human ALDH1A1 protein | Human |
| GM-Tg-rg-TA001-Ag-1/ GM-Tg-rg-TA001-Ag-2 | Rat ALDH1A1 protein | Rat |
| GM-Tg-mg-TA001-Ag-1/ GM-Tg-mg-TA001-Ag-2 | Mouse ALDH1A1 protein | Mouse |
| GM-Tg-cynog-TA001-Ag-1/ GM-Tg-cynog-TA001-Ag-2 | Cynomolgus/Rhesus macaque ALDH1A1 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-TA001-Ag-1/ GM-Tg-felg-TA001-Ag-2 | Feline ALDH1A1 protein | Feline |
| GM-Tg-cang-TA001-Ag-1/ GM-Tg-cang-TA001-Ag-2 | Canine ALDH1A1 protein | Canine |
| GM-Tg-bovg-TA001-Ag-1/ GM-Tg-bovg-TA001-Ag-2 | Bovine ALDH1A1 protein | Bovine |
| GM-Tg-equg-TA001-Ag-1/ GM-Tg-equg-TA001-Ag-2 | Equine ALDH1A1 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-TA001-Ag-1/ GM-Tg-hg-TA001-Ag-2;
GM-Tg-rg-TA001-Ag-1/ GM-Tg-rg-TA001-Ag-2;
GM-Tg-mg-TA001-Ag-1/ GM-Tg-mg-TA001-Ag-2; GM-Tg-cynog-TA001-Ag-1/ GM-Tg-cynog-TA001-Ag-2; GM-Tg-felg-TA001-Ag-1/ GM-Tg-felg-TA001-Ag-2; GM-Tg-cang-TA001-Ag-1/ GM-Tg-cang-TA001-Ag-2; GM-Tg-bovg-TA001-Ag-1/ GM-Tg-bovg-TA001-Ag-2; GM-Tg-equg-TA001-Ag-1/ GM-Tg-equg-TA001-Ag-2 |
| Products Name | ALDH1A1 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | ALDH1A1 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ALDH1A1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.