Recombinant multi-species PBK protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PBK protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a serine/threonine protein kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. The encoded protein may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis. Overexpression of this gene has been implicated in tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
The Alternative Names of target: 2810434B10Rik,CT84,Cancer/testis antigen 84 (CT84),D14Ertd732e,HEL164,Lymphokine-activated killer T-cell-originated protein kinase,MAPKK-like protein kinase,Nori-3,PBK,PDZ-binding kinase,Pbk,SPK,Spermatogenesis-related protein kinase (SPK),T-LAK cell-originated protein kinase,TOPK

Target products collectionGo to PBK products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T98642-Ag-1/ GM-Tg-hg-T98642-Ag-2 Human PBK protein Human
GM-Tg-rg-T98642-Ag-1/ GM-Tg-rg-T98642-Ag-2 Rat PBK protein Rat
GM-Tg-mg-T98642-Ag-1/ GM-Tg-mg-T98642-Ag-2 Mouse PBK protein Mouse
GM-Tg-cynog-T98642-Ag-1/ GM-Tg-cynog-T98642-Ag-2 Cynomolgus/Rhesus macaque PBK protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T98642-Ag-1/ GM-Tg-felg-T98642-Ag-2 Feline PBK protein Feline
GM-Tg-cang-T98642-Ag-1/ GM-Tg-cang-T98642-Ag-2 Canine PBK protein Canine
GM-Tg-bovg-T98642-Ag-1/ GM-Tg-bovg-T98642-Ag-2 Bovine PBK protein Bovine
GM-Tg-equg-T98642-Ag-1/ GM-Tg-equg-T98642-Ag-2 Equine PBK protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T98642-Ag-1/ GM-Tg-hg-T98642-Ag-2; GM-Tg-rg-T98642-Ag-1/ GM-Tg-rg-T98642-Ag-2;
GM-Tg-mg-T98642-Ag-1/ GM-Tg-mg-T98642-Ag-2; GM-Tg-cynog-T98642-Ag-1/ GM-Tg-cynog-T98642-Ag-2;
GM-Tg-felg-T98642-Ag-1/ GM-Tg-felg-T98642-Ag-2; GM-Tg-cang-T98642-Ag-1/ GM-Tg-cang-T98642-Ag-2;
GM-Tg-bovg-T98642-Ag-1/ GM-Tg-bovg-T98642-Ag-2; GM-Tg-equg-T98642-Ag-1/ GM-Tg-equg-T98642-Ag-2
Products Name PBK protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PBK
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PBK protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.