Recombinant multi-species AURKC protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine AURKC protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
The Alternative Names of target: AIE1,AIE2,AIK3,ARK-3,ARK3,AURKC,AurC,Aurkc,Aurora 3,Aurora kinase C,Aurora-related kinase 3),Aurora/IPL1-related kinase 3 (ARK-3,Aurora/IPL1/Eg2 protein 2,HEL-S-90,IAK3,SPGF5,STK13,Serine/threonine-protein kinase 13,Serine/threonine-protein kinase aurora-C,Stk13,aurora-C

Target products collectionGo to AURKC products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T97592-Ag-1/ GM-Tg-hg-T97592-Ag-2 Human AURKC protein Human
GM-Tg-rg-T97592-Ag-1/ GM-Tg-rg-T97592-Ag-2 Rat AURKC protein Rat
GM-Tg-mg-T97592-Ag-1/ GM-Tg-mg-T97592-Ag-2 Mouse AURKC protein Mouse
GM-Tg-cynog-T97592-Ag-1/ GM-Tg-cynog-T97592-Ag-2 Cynomolgus/Rhesus macaque AURKC protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T97592-Ag-1/ GM-Tg-felg-T97592-Ag-2 Feline AURKC protein Feline
GM-Tg-cang-T97592-Ag-1/ GM-Tg-cang-T97592-Ag-2 Canine AURKC protein Canine
GM-Tg-bovg-T97592-Ag-1/ GM-Tg-bovg-T97592-Ag-2 Bovine AURKC protein Bovine
GM-Tg-equg-T97592-Ag-1/ GM-Tg-equg-T97592-Ag-2 Equine AURKC protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T97592-Ag-1/ GM-Tg-hg-T97592-Ag-2; GM-Tg-rg-T97592-Ag-1/ GM-Tg-rg-T97592-Ag-2;
GM-Tg-mg-T97592-Ag-1/ GM-Tg-mg-T97592-Ag-2; GM-Tg-cynog-T97592-Ag-1/ GM-Tg-cynog-T97592-Ag-2;
GM-Tg-felg-T97592-Ag-1/ GM-Tg-felg-T97592-Ag-2; GM-Tg-cang-T97592-Ag-1/ GM-Tg-cang-T97592-Ag-2;
GM-Tg-bovg-T97592-Ag-1/ GM-Tg-bovg-T97592-Ag-2; GM-Tg-equg-T97592-Ag-1/ GM-Tg-equg-T97592-Ag-2
Products Name AURKC protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name AURKC
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine AURKC protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.