Recombinant multi-species TCF3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TCF3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the E protein (class I) family of helix-loop-helix transcription factors. E proteins activate transcription by binding to regulatory E-box sequences on target genes as heterodimers or homodimers, and are inhibited by heterodimerization with inhibitor of DNA-binding (class IV) helix-loop-helix proteins. E proteins play a critical role in lymphopoiesis, and the encoded protein is required for B and T lymphocyte development. Deletion of this gene or diminished activity of the encoded protein may play a role in lymphoid malignancies. This gene is also involved in several chromosomal translocations that are associated with lymphoid malignancies including pre-B-cell acute lymphoblastic leukemia (t(1;19), with PBX1), childhood leukemia (t(19;19), with TFPT) and acute leukemia (t(12;19), with ZNF384). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, Sep 2011]
The Alternative Names of target: A1,AGM8,AGM8A,AGM8B,ALF2,Class B basic helix-loop-helix protein 21 (bHLHb21),E12,E12/E47,E2A,E47,ITF1,Immunoglobulin enhancer-binding factor E12/E47,Immunoglobulin transcription factor 1,KA1,Kappa-E2-binding factor,ME2,Pan1,Pan2,TCF-3,TCF3,Tcf3,Tcfe2a,Transcription factor 3 (TCF-3),Transcription factor E2-alpha,Transcription factor ITF-1,VDIR,bHLHb21,p75

Target products collectionGo to TCF3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T95715-Ag-1/ GM-Tg-hg-T95715-Ag-2 Human TCF3 protein Human
GM-Tg-rg-T95715-Ag-1/ GM-Tg-rg-T95715-Ag-2 Rat TCF3 protein Rat
GM-Tg-mg-T95715-Ag-1/ GM-Tg-mg-T95715-Ag-2 Mouse TCF3 protein Mouse
GM-Tg-cynog-T95715-Ag-1/ GM-Tg-cynog-T95715-Ag-2 Cynomolgus/Rhesus macaque TCF3 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T95715-Ag-1/ GM-Tg-felg-T95715-Ag-2 Feline TCF3 protein Feline
GM-Tg-cang-T95715-Ag-1/ GM-Tg-cang-T95715-Ag-2 Canine TCF3 protein Canine
GM-Tg-bovg-T95715-Ag-1/ GM-Tg-bovg-T95715-Ag-2 Bovine TCF3 protein Bovine
GM-Tg-equg-T95715-Ag-1/ GM-Tg-equg-T95715-Ag-2 Equine TCF3 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T95715-Ag-1/ GM-Tg-hg-T95715-Ag-2; GM-Tg-rg-T95715-Ag-1/ GM-Tg-rg-T95715-Ag-2;
GM-Tg-mg-T95715-Ag-1/ GM-Tg-mg-T95715-Ag-2; GM-Tg-cynog-T95715-Ag-1/ GM-Tg-cynog-T95715-Ag-2;
GM-Tg-felg-T95715-Ag-1/ GM-Tg-felg-T95715-Ag-2; GM-Tg-cang-T95715-Ag-1/ GM-Tg-cang-T95715-Ag-2;
GM-Tg-bovg-T95715-Ag-1/ GM-Tg-bovg-T95715-Ag-2; GM-Tg-equg-T95715-Ag-1/ GM-Tg-equg-T95715-Ag-2
Products Name TCF3 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name TCF3
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TCF3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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