Recombinant multi-species CRLF1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CRLF1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the cytokine type I receptor family. The protein forms a secreted complex with cardiotrophin-like cytokine factor 1 and acts on cells expressing ciliary neurotrophic factor receptors. The complex can promote survival of neuronal cells. Mutations in this gene result in Crisponi syndrome and cold-induced sweating syndrome. [provided by RefSeq, Oct 2009]
The Alternative Names of target: CRLF1,Cytokine receptor-like factor 1,Cytokine-like factor 1 (CLF-1), ZcytoR5,CLF,NR6,CISS,CISS1,CLF-1,zcytor5

Target products collectionGo to CRLF1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T94313-Ab-1/ GM-Tg-hg-T94313-Ab-2 Human CRLF1 protein Human
GM-Tg-rg-T94313-Ab-1/ GM-Tg-rg-T94313-Ab-2 Rat CRLF1 protein Rat
GM-Tg-mg-T94313-Ab-1/ GM-Tg-mg-T94313-Ab-2 Mouse CRLF1 protein Mouse
GM-Tg-cynog-T94313-Ab-1/ GM-Tg-cynog-T94313-Ab-2 Cynomolgus/Rhesus macaque CRLF1 monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-T94313-Ab-1/ GM-Tg-felg-T94313-Ab-2 Feline CRLF1 protein Feline
GM-Tg-cang-T94313-Ab-1/ GM-Tg-cang-T94313-Ab-2 Canine CRLF1 protein Canine
GM-Tg-bovg-T94313-Ab-1/ GM-Tg-bovg-T94313-Ab-2 Bovine CRLF1 protein Bovine
GM-Tg-equg-T94313-Ab-1/ GM-Tg-equg-T94313-Ab-2 Equine CRLF1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T94313-Ab-1/ GM-Tg-hg-T94313-Ab-2; GM-Tg-rg-T94313-Ab-1/ GM-Tg-rg-T94313-Ab-2;
GM-Tg-mg-T94313-Ab-1/ GM-Tg-mg-T94313-Ab-2; GM-Tg-cynog-T94313-Ab-1/ GM-Tg-cynog-T94313-Ab-2;
GM-Tg-felg-T94313-Ab-1/ GM-Tg-felg-T94313-Ab-2; GM-Tg-cang-T94313-Ab-1/ GM-Tg-cang-T94313-Ab-2;
GM-Tg-bovg-T94313-Ab-1/ GM-Tg-bovg-T94313-Ab-2; GM-Tg-equg-T94313-Ab-1/ GM-Tg-equg-T94313-Ab-2
Products Name CRLF1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CRLF1
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CRLF1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.