Recombinant multi-species NR4A3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NR4A3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcriptional activator. The protein can efficiently bind the NGFI-B Response Element (NBRE). Three different versions of extraskeletal myxoid chondrosarcomas (EMCs) are the result of reciprocal translocations between this gene and other genes. The translocation breakpoints are associated with Nuclear Receptor Subfamily 4, Group A, Member 3 (on chromosome 9) and either Ewing Sarcome Breakpoint Region 1 (on chromosome 22), RNA Polymerase II, TATA Box-Binding Protein-Associated Factor, 68-KD (on chromosome 17), or Transcription factor 12 (on chromosome 15). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
The Alternative Names of target: CHN,CSMF,MINOR,Mitogen-induced nuclear orphan receptor,NOR-1,NOR-2,NOR1,NR4A3,Neuron-derived orphan receptor 1,Nor1,Nr4a3,Nuclear hormone receptor NOR-1,Nuclear receptor subfamily 4 group A member 3,TEC

Target products collectionGo to NR4A3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T93949-Ag-1/ GM-Tg-hg-T93949-Ag-2 Human NR4A3 protein Human
GM-Tg-rg-T93949-Ag-1/ GM-Tg-rg-T93949-Ag-2 Rat NR4A3 protein Rat
GM-Tg-mg-T93949-Ag-1/ GM-Tg-mg-T93949-Ag-2 Mouse NR4A3 protein Mouse
GM-Tg-cynog-T93949-Ag-1/ GM-Tg-cynog-T93949-Ag-2 Cynomolgus/Rhesus macaque NR4A3 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T93949-Ag-1/ GM-Tg-felg-T93949-Ag-2 Feline NR4A3 protein Feline
GM-Tg-cang-T93949-Ag-1/ GM-Tg-cang-T93949-Ag-2 Canine NR4A3 protein Canine
GM-Tg-bovg-T93949-Ag-1/ GM-Tg-bovg-T93949-Ag-2 Bovine NR4A3 protein Bovine
GM-Tg-equg-T93949-Ag-1/ GM-Tg-equg-T93949-Ag-2 Equine NR4A3 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T93949-Ag-1/ GM-Tg-hg-T93949-Ag-2; GM-Tg-rg-T93949-Ag-1/ GM-Tg-rg-T93949-Ag-2;
GM-Tg-mg-T93949-Ag-1/ GM-Tg-mg-T93949-Ag-2; GM-Tg-cynog-T93949-Ag-1/ GM-Tg-cynog-T93949-Ag-2;
GM-Tg-felg-T93949-Ag-1/ GM-Tg-felg-T93949-Ag-2; GM-Tg-cang-T93949-Ag-1/ GM-Tg-cang-T93949-Ag-2;
GM-Tg-bovg-T93949-Ag-1/ GM-Tg-bovg-T93949-Ag-2; GM-Tg-equg-T93949-Ag-1/ GM-Tg-equg-T93949-Ag-2
Products Name NR4A3 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name NR4A3
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NR4A3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.