Recombinant multi-species MALT1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MALT1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a caspase-like protease that plays a role in BCL10-induced activation of NF-kappaB. The protein is a component of the CARMA1-BCL10-MALT1 (CBM) signalosome that triggers NF-kappaB signaling and lymphoctye activation following antigen-receptor stimulation. Mutations in this gene result in immunodeficiency 12 (IMD12). This gene has been found to be recurrently rearranged in chromosomal translocations with other genes in mucosa-associated lymphoid tissue lymphomas, including a t(11;18)(q21;q21) translocation with the baculoviral IAP repeat-containing protein 3 (also known as apoptosis inhibitor 2) locus [BIRC3(API2)-MALT1], and a t(14;18)(q32;q21) translocation with the immunoglobulin heavy chain locus (IGH-MALT1). Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2018]
The Alternative Names of target: A630046N12,D430033E09Rik,IMD12,MALT lymphoma-associated translocation,MALT1,MLT,MLT1,Malt1,Mucosa-associated lymphoid tissue lymphoma translocation protein 1,PCASP1,Paracaspase,Pcasp1

Target products collectionGo to MALT1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T92678-Ag-1/ GM-Tg-hg-T92678-Ag-2 Human MALT1 protein Human
GM-Tg-rg-T92678-Ag-1/ GM-Tg-rg-T92678-Ag-2 Rat MALT1 protein Rat
GM-Tg-mg-T92678-Ag-1/ GM-Tg-mg-T92678-Ag-2 Mouse MALT1 protein Mouse
GM-Tg-cynog-T92678-Ag-1/ GM-Tg-cynog-T92678-Ag-2 Cynomolgus/Rhesus macaque MALT1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T92678-Ag-1/ GM-Tg-felg-T92678-Ag-2 Feline MALT1 protein Feline
GM-Tg-cang-T92678-Ag-1/ GM-Tg-cang-T92678-Ag-2 Canine MALT1 protein Canine
GM-Tg-bovg-T92678-Ag-1/ GM-Tg-bovg-T92678-Ag-2 Bovine MALT1 protein Bovine
GM-Tg-equg-T92678-Ag-1/ GM-Tg-equg-T92678-Ag-2 Equine MALT1 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T92678-Ag-1/ GM-Tg-hg-T92678-Ag-2; GM-Tg-rg-T92678-Ag-1/ GM-Tg-rg-T92678-Ag-2;
GM-Tg-mg-T92678-Ag-1/ GM-Tg-mg-T92678-Ag-2; GM-Tg-cynog-T92678-Ag-1/ GM-Tg-cynog-T92678-Ag-2;
GM-Tg-felg-T92678-Ag-1/ GM-Tg-felg-T92678-Ag-2; GM-Tg-cang-T92678-Ag-1/ GM-Tg-cang-T92678-Ag-2;
GM-Tg-bovg-T92678-Ag-1/ GM-Tg-bovg-T92678-Ag-2; GM-Tg-equg-T92678-Ag-1/ GM-Tg-equg-T92678-Ag-2
Products Name MALT1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name MALT1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MALT1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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