Recombinant multi-species MYH2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MYH2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Myosins are actin-based motor proteins that function in the generation of mechanical force in eukaryotic cells. Muscle myosins are heterohexamers composed of 2 myosin heavy chains and 2 pairs of nonidentical myosin light chains. This gene encodes a member of the class II or conventional myosin heavy chains, and functions in skeletal muscle contraction. This gene is found in a cluster of myosin heavy chain genes on chromosome 17. A mutation in this gene results in inclusion body myopathy-3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2009]
The Alternative Names of target: CMYO6,CMYP6,IBM3,MHC2A,MYH2,MYH2A,MYHSA2,MYHas8,MYPOP,MyHC-2A,MyHC-2a,MyHC-IIA,MyHC-IIa,Myh1,Myh2,Myh2a,Myhs-f,Myhs-f1,Myhsf1,Myosin heavy chain,Myosin heavy chain 2,Myosin heavy chain 2a (MyHC-2a),Myosin heavy chain IIa (MyHC-IIa),Myosin-2,adult 2,skeletal muscle

Target products collectionGo to MYH2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T90071-Ag-1/ GM-Tg-hg-T90071-Ag-2 Human MYH2 protein Human
GM-Tg-rg-T90071-Ag-1/ GM-Tg-rg-T90071-Ag-2 Rat MYH2 protein Rat
GM-Tg-mg-T90071-Ag-1/ GM-Tg-mg-T90071-Ag-2 Mouse MYH2 protein Mouse
GM-Tg-cynog-T90071-Ag-1/ GM-Tg-cynog-T90071-Ag-2 Cynomolgus/Rhesus macaque MYH2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T90071-Ag-1/ GM-Tg-felg-T90071-Ag-2 Feline MYH2 protein Feline
GM-Tg-cang-T90071-Ag-1/ GM-Tg-cang-T90071-Ag-2 Canine MYH2 protein Canine
GM-Tg-bovg-T90071-Ag-1/ GM-Tg-bovg-T90071-Ag-2 Bovine MYH2 protein Bovine
GM-Tg-equg-T90071-Ag-1/ GM-Tg-equg-T90071-Ag-2 Equine MYH2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T90071-Ag-1/ GM-Tg-hg-T90071-Ag-2; GM-Tg-rg-T90071-Ag-1/ GM-Tg-rg-T90071-Ag-2;
GM-Tg-mg-T90071-Ag-1/ GM-Tg-mg-T90071-Ag-2; GM-Tg-cynog-T90071-Ag-1/ GM-Tg-cynog-T90071-Ag-2;
GM-Tg-felg-T90071-Ag-1/ GM-Tg-felg-T90071-Ag-2; GM-Tg-cang-T90071-Ag-1/ GM-Tg-cang-T90071-Ag-2;
GM-Tg-bovg-T90071-Ag-1/ GM-Tg-bovg-T90071-Ag-2; GM-Tg-equg-T90071-Ag-1/ GM-Tg-equg-T90071-Ag-2
Products Name MYH2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name MYH2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MYH2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.