Recombinant multi-species Ferritin heavy chain/FTH1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Ferritin heavy chain/FTH1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
The Alternative Names of target: Cell proliferation-inducing gene 15 protein,FHC,FTH,FTH1,FTHL6,Ferritin H subunit,Ferritin heavy chain,Fth,Fth1,HFE5,HFt,MFH,NBIA9,PIG15,PLIF

Target products collectionGo to Ferritin heavy chain/FTH1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T89873-Ag-1/ GM-Tg-hg-T89873-Ag-2 Human Ferritin heavy chain/FTH1 protein Human
GM-Tg-rg-T89873-Ag-1/ GM-Tg-rg-T89873-Ag-2 Rat Ferritin heavy chain/FTH1 protein Rat
GM-Tg-mg-T89873-Ag-1/ GM-Tg-mg-T89873-Ag-2 Mouse Ferritin heavy chain/FTH1 protein Mouse
GM-Tg-cynog-T89873-Ag-1/ GM-Tg-cynog-T89873-Ag-2 Cynomolgus/Rhesus macaque Ferritin heavy chain/FTH1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T89873-Ag-1/ GM-Tg-felg-T89873-Ag-2 Feline Ferritin heavy chain/FTH1 protein Feline
GM-Tg-cang-T89873-Ag-1/ GM-Tg-cang-T89873-Ag-2 Canine Ferritin heavy chain/FTH1 protein Canine
GM-Tg-bovg-T89873-Ag-1/ GM-Tg-bovg-T89873-Ag-2 Bovine Ferritin heavy chain/FTH1 protein Bovine
GM-Tg-equg-T89873-Ag-1/ GM-Tg-equg-T89873-Ag-2 Equine Ferritin heavy chain/FTH1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T89873-Ag-1/ GM-Tg-hg-T89873-Ag-2; GM-Tg-rg-T89873-Ag-1/ GM-Tg-rg-T89873-Ag-2;
GM-Tg-mg-T89873-Ag-1/ GM-Tg-mg-T89873-Ag-2; GM-Tg-cynog-T89873-Ag-1/ GM-Tg-cynog-T89873-Ag-2;
GM-Tg-felg-T89873-Ag-1/ GM-Tg-felg-T89873-Ag-2; GM-Tg-cang-T89873-Ag-1/ GM-Tg-cang-T89873-Ag-2;
GM-Tg-bovg-T89873-Ag-1/ GM-Tg-bovg-T89873-Ag-2; GM-Tg-equg-T89873-Ag-1/ GM-Tg-equg-T89873-Ag-2
Products Name Ferritin heavy chain/FTH1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name Ferritin heavy chain/FTH1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Ferritin heavy chain/FTH1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.