Recombinant multi-species SOD Mn protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SOD Mn protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. [provided by RefSeq, Apr 2016]
The Alternative Names of target: GC1,GClnc1,IPO-B,IPOB,MNSOD,MVCD6,Mn-SOD,MnSOD,SOD Mn,SOD2,SOD2X1,SOD2X2,Sod-2,Sod2,Superoxide dismutase [Mn],lncRNA-GC1,mitochondrial

Target products collectionGo to SOD Mn products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T89147-Ag-1/ GM-Tg-hg-T89147-Ag-2 Human SOD Mn protein Human
GM-Tg-rg-T89147-Ag-1/ GM-Tg-rg-T89147-Ag-2 Rat SOD Mn protein Rat
GM-Tg-mg-T89147-Ag-1/ GM-Tg-mg-T89147-Ag-2 Mouse SOD Mn protein Mouse
GM-Tg-cynog-T89147-Ag-1/ GM-Tg-cynog-T89147-Ag-2 Cynomolgus/Rhesus macaque SOD Mn protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T89147-Ag-1/ GM-Tg-felg-T89147-Ag-2 Feline SOD Mn protein Feline
GM-Tg-cang-T89147-Ag-1/ GM-Tg-cang-T89147-Ag-2 Canine SOD Mn protein Canine
GM-Tg-bovg-T89147-Ag-1/ GM-Tg-bovg-T89147-Ag-2 Bovine SOD Mn protein Bovine
GM-Tg-equg-T89147-Ag-1/ GM-Tg-equg-T89147-Ag-2 Equine SOD Mn protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T89147-Ag-1/ GM-Tg-hg-T89147-Ag-2; GM-Tg-rg-T89147-Ag-1/ GM-Tg-rg-T89147-Ag-2;
GM-Tg-mg-T89147-Ag-1/ GM-Tg-mg-T89147-Ag-2; GM-Tg-cynog-T89147-Ag-1/ GM-Tg-cynog-T89147-Ag-2;
GM-Tg-felg-T89147-Ag-1/ GM-Tg-felg-T89147-Ag-2; GM-Tg-cang-T89147-Ag-1/ GM-Tg-cang-T89147-Ag-2;
GM-Tg-bovg-T89147-Ag-1/ GM-Tg-bovg-T89147-Ag-2; GM-Tg-equg-T89147-Ag-1/ GM-Tg-equg-T89147-Ag-2
Products Name SOD Mn protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name SOD Mn
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SOD Mn protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.