Recombinant multi-species Prealbumin/transthyretin/TTR protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Prealbumin/transthyretin/TTR protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes one of the three prealbumins, which include alpha-1-antitrypsin, transthyretin and orosomucoid. The encoded protein, transthyretin, is a homo-tetrameric carrier protein, which transports thyroid hormones in the plasma and cerebrospinal fluid. It is also involved in the transport of retinol (vitamin A) in the plasma by associating with retinol-binding protein. The protein may also be involved in other intracellular processes including proteolysis, nerve regeneration, autophagy and glucose homeostasis. Mutations in this gene are associated with amyloid deposition, predominantly affecting peripheral nerves or the heart, while a small percentage of the gene mutations are non-amyloidogenic. The mutations are implicated in the etiology of several diseases, including amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis and carpal tunnel syndrome. [provided by RefSeq, Aug 2017]
The Alternative Names of target: ATTR,CTS,CTS1,HEL111,HsT2651,Lr1,PALB,Prealbumin,TBPA,TT,TTN,TTR,TTR1,Tbpa,Transthyretin,Ttr,prealbumin,transthyretin

Target products collectionGo to Prealbumin/transthyretin/TTR products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T86462-Ag-1/ GM-Tg-hg-T86462-Ag-2 Human Prealbumin/transthyretin/TTR protein Human
GM-Tg-rg-T86462-Ag-1/ GM-Tg-rg-T86462-Ag-2 Rat Prealbumin/transthyretin/TTR protein Rat
GM-Tg-mg-T86462-Ag-1/ GM-Tg-mg-T86462-Ag-2 Mouse Prealbumin/transthyretin/TTR protein Mouse
GM-Tg-cynog-T86462-Ag-1/ GM-Tg-cynog-T86462-Ag-2 Cynomolgus/Rhesus macaque Prealbumin/transthyretin/TTR protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T86462-Ag-1/ GM-Tg-felg-T86462-Ag-2 Feline Prealbumin/transthyretin/TTR protein Feline
GM-Tg-cang-T86462-Ag-1/ GM-Tg-cang-T86462-Ag-2 Canine Prealbumin/transthyretin/TTR protein Canine
GM-Tg-bovg-T86462-Ag-1/ GM-Tg-bovg-T86462-Ag-2 Bovine Prealbumin/transthyretin/TTR protein Bovine
GM-Tg-equg-T86462-Ag-1/ GM-Tg-equg-T86462-Ag-2 Equine Prealbumin/transthyretin/TTR protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T86462-Ag-1/ GM-Tg-hg-T86462-Ag-2; GM-Tg-rg-T86462-Ag-1/ GM-Tg-rg-T86462-Ag-2;
GM-Tg-mg-T86462-Ag-1/ GM-Tg-mg-T86462-Ag-2; GM-Tg-cynog-T86462-Ag-1/ GM-Tg-cynog-T86462-Ag-2;
GM-Tg-felg-T86462-Ag-1/ GM-Tg-felg-T86462-Ag-2; GM-Tg-cang-T86462-Ag-1/ GM-Tg-cang-T86462-Ag-2;
GM-Tg-bovg-T86462-Ag-1/ GM-Tg-bovg-T86462-Ag-2; GM-Tg-equg-T86462-Ag-1/ GM-Tg-equg-T86462-Ag-2
Products Name Prealbumin/transthyretin/TTR protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name Prealbumin/transthyretin/TTR
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Prealbumin/transthyretin/TTR protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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