Recombinant multi-species CYR61/CCN1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CYR61/CCN1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The secreted protein encoded by this gene is growth factor-inducible and promotes the adhesion of endothelial cells. The encoded protein interacts with several integrins and with heparan sulfate proteoglycan. This protein also plays a role in cell proliferation, differentiation, angiogenesis, apoptosis, and extracellular matrix formation. [provided by RefSeq, Sep 2011]
The Alternative Names of target: CCN family member 1,CCN1,CYR61,Ccn1,Cellular communication network factor 1,Cyr61,Cysteine-rich angiogenic inducer 61,GIG1,IGF-binding protein 10,IGFBP-10),IGFBP10,Igfbp10,Insulin-like growth factor-binding protein 10 (IBP-10,Protein CYR61,Protein GIG1

Target products collectionGo to CYR61/CCN1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T85289-Ag-1/ GM-Tg-hg-T85289-Ag-2 Human CYR61/CCN1 protein Human
GM-Tg-rg-T85289-Ag-1/ GM-Tg-rg-T85289-Ag-2 Rat CYR61/CCN1 protein Rat
GM-Tg-mg-T85289-Ag-1/ GM-Tg-mg-T85289-Ag-2 Mouse CYR61/CCN1 protein Mouse
GM-Tg-cynog-T85289-Ag-1/ GM-Tg-cynog-T85289-Ag-2 Cynomolgus/Rhesus macaque CYR61/CCN1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T85289-Ag-1/ GM-Tg-felg-T85289-Ag-2 Feline CYR61/CCN1 protein Feline
GM-Tg-cang-T85289-Ag-1/ GM-Tg-cang-T85289-Ag-2 Canine CYR61/CCN1 protein Canine
GM-Tg-bovg-T85289-Ag-1/ GM-Tg-bovg-T85289-Ag-2 Bovine CYR61/CCN1 protein Bovine
GM-Tg-equg-T85289-Ag-1/ GM-Tg-equg-T85289-Ag-2 Equine CYR61/CCN1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T85289-Ag-1/ GM-Tg-hg-T85289-Ag-2; GM-Tg-rg-T85289-Ag-1/ GM-Tg-rg-T85289-Ag-2;
GM-Tg-mg-T85289-Ag-1/ GM-Tg-mg-T85289-Ag-2; GM-Tg-cynog-T85289-Ag-1/ GM-Tg-cynog-T85289-Ag-2;
GM-Tg-felg-T85289-Ag-1/ GM-Tg-felg-T85289-Ag-2; GM-Tg-cang-T85289-Ag-1/ GM-Tg-cang-T85289-Ag-2;
GM-Tg-bovg-T85289-Ag-1/ GM-Tg-bovg-T85289-Ag-2; GM-Tg-equg-T85289-Ag-1/ GM-Tg-equg-T85289-Ag-2
Products Name CYR61/CCN1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CYR61/CCN1
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CYR61/CCN1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.