Recombinant multi-species JAB1/COPS5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine JAB1/COPS5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of  cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors. [provided by RefSeq, Jul 2008]
The Alternative Names of target: COP9 signalosome complex subunit 5,COPS5,CSN5,Cops5,JAB1,Jab1,Jun activation domain-binding protein 1,MOV-34,Mov34,SGN5,Sgn5,Signalosome subunit 5

Target products collectionGo to JAB1/COPS5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T84791-Ag-1/ GM-Tg-hg-T84791-Ag-2 Human JAB1/COPS5 protein Human
GM-Tg-rg-T84791-Ag-1/ GM-Tg-rg-T84791-Ag-2 Rat JAB1/COPS5 protein Rat
GM-Tg-mg-T84791-Ag-1/ GM-Tg-mg-T84791-Ag-2 Mouse JAB1/COPS5 protein Mouse
GM-Tg-cynog-T84791-Ag-1/ GM-Tg-cynog-T84791-Ag-2 Cynomolgus/Rhesus macaque JAB1/COPS5 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T84791-Ag-1/ GM-Tg-felg-T84791-Ag-2 Feline JAB1/COPS5 protein Feline
GM-Tg-cang-T84791-Ag-1/ GM-Tg-cang-T84791-Ag-2 Canine JAB1/COPS5 protein Canine
GM-Tg-bovg-T84791-Ag-1/ GM-Tg-bovg-T84791-Ag-2 Bovine JAB1/COPS5 protein Bovine
GM-Tg-equg-T84791-Ag-1/ GM-Tg-equg-T84791-Ag-2 Equine JAB1/COPS5 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T84791-Ag-1/ GM-Tg-hg-T84791-Ag-2; GM-Tg-rg-T84791-Ag-1/ GM-Tg-rg-T84791-Ag-2;
GM-Tg-mg-T84791-Ag-1/ GM-Tg-mg-T84791-Ag-2; GM-Tg-cynog-T84791-Ag-1/ GM-Tg-cynog-T84791-Ag-2;
GM-Tg-felg-T84791-Ag-1/ GM-Tg-felg-T84791-Ag-2; GM-Tg-cang-T84791-Ag-1/ GM-Tg-cang-T84791-Ag-2;
GM-Tg-bovg-T84791-Ag-1/ GM-Tg-bovg-T84791-Ag-2; GM-Tg-equg-T84791-Ag-1/ GM-Tg-equg-T84791-Ag-2
Products Name JAB1/COPS5 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name JAB1/COPS5
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine JAB1/COPS5 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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