Recombinant multi-species HGF protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HGF protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a protein that binds to the hepatocyte growth factor receptor to regulate cell growth, cell motility and morphogenesis in numerous cell and tissue types. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate alpha and beta chains, which form the mature heterodimer. This protein is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. This protein also plays a role in angiogenesis, tumorogenesis, and tissue regeneration. Although the encoded protein is a member of the peptidase S1 family of serine proteases, it lacks peptidase activity. Mutations in this gene are associated with nonsyndromic hearing loss. [provided by RefSeq, Nov 2015]
The Alternative Names of target: C230052L06Rik,DFNB39,F-TCF,HGF,HGF/SF,HGFB,HPTA,Hepatocyte growth factor,Hepatopoietin-A,Hgf,NK1,NK2,SF,SF/HGF,Scatter factor (SF)

Target products collectionGo to HGF products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T83797-Ag-1/ GM-Tg-hg-T83797-Ag-2 Human HGF protein Human
GM-Tg-rg-T83797-Ag-1/ GM-Tg-rg-T83797-Ag-2 Rat HGF protein Rat
GM-Tg-mg-T83797-Ag-1/ GM-Tg-mg-T83797-Ag-2 Mouse HGF protein Mouse
GM-Tg-cynog-T83797-Ag-1/ GM-Tg-cynog-T83797-Ag-2 Cynomolgus/Rhesus macaque HGF protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T83797-Ag-1/ GM-Tg-felg-T83797-Ag-2 Feline HGF protein Feline
GM-Tg-cang-T83797-Ag-1/ GM-Tg-cang-T83797-Ag-2 Canine HGF protein Canine
GM-Tg-bovg-T83797-Ag-1/ GM-Tg-bovg-T83797-Ag-2 Bovine HGF protein Bovine
GM-Tg-equg-T83797-Ag-1/ GM-Tg-equg-T83797-Ag-2 Equine HGF protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T83797-Ag-1/ GM-Tg-hg-T83797-Ag-2; GM-Tg-rg-T83797-Ag-1/ GM-Tg-rg-T83797-Ag-2;
GM-Tg-mg-T83797-Ag-1/ GM-Tg-mg-T83797-Ag-2; GM-Tg-cynog-T83797-Ag-1/ GM-Tg-cynog-T83797-Ag-2;
GM-Tg-felg-T83797-Ag-1/ GM-Tg-felg-T83797-Ag-2; GM-Tg-cang-T83797-Ag-1/ GM-Tg-cang-T83797-Ag-2;
GM-Tg-bovg-T83797-Ag-1/ GM-Tg-bovg-T83797-Ag-2; GM-Tg-equg-T83797-Ag-1/ GM-Tg-equg-T83797-Ag-2
Products Name HGF protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name HGF
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HGF protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.