Recombinant multi-species COL6A3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine COL6A3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes the alpha-3 chain, one of the three alpha chains of type VI collagen, a beaded filament collagen found in most connective tissues. The alpha-3 chain of type VI collagen is much larger than the alpha-1 and -2 chains. This difference in size is largely due to an increase in the number of subdomains, similar to von Willebrand Factor type A domains, that are found in the amino terminal globular domain of all the alpha chains. These domains have been shown to bind extracellular matrix proteins, an interaction that explains the importance of this collagen in organizing matrix components. Mutations in the type VI collagen genes are associated with Bethlem myopathy, a rare autosomal dominant proximal myopathy with early childhood onset. Mutations in this gene are also a cause of Ullrich congenital muscular dystrophy, also referred to as Ullrich scleroatonic muscular dystrophy, an autosomal recessive congenital myopathy that is more severe than Bethlem myopathy. Multiple transcript variants have been identified, but the full-length nature of only some of these variants has been described. [provided by RefSeq, Jun 2009]
The Alternative Names of target: BTHLM1,BTHLM1C,COL6A3,Col6a-3,Col6a3,Collagen alpha-3(VI) chain,DYT27,UCMD1,UCMD1C

Target products collectionGo to COL6A3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T83450-Ag-1/ GM-Tg-hg-T83450-Ag-2 Human COL6A3 protein Human
GM-Tg-rg-T83450-Ag-1/ GM-Tg-rg-T83450-Ag-2 Rat COL6A3 protein Rat
GM-Tg-mg-T83450-Ag-1/ GM-Tg-mg-T83450-Ag-2 Mouse COL6A3 protein Mouse
GM-Tg-cynog-T83450-Ag-1/ GM-Tg-cynog-T83450-Ag-2 Cynomolgus/Rhesus macaque COL6A3 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T83450-Ag-1/ GM-Tg-felg-T83450-Ag-2 Feline COL6A3 protein Feline
GM-Tg-cang-T83450-Ag-1/ GM-Tg-cang-T83450-Ag-2 Canine COL6A3 protein Canine
GM-Tg-bovg-T83450-Ag-1/ GM-Tg-bovg-T83450-Ag-2 Bovine COL6A3 protein Bovine
GM-Tg-equg-T83450-Ag-1/ GM-Tg-equg-T83450-Ag-2 Equine COL6A3 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T83450-Ag-1/ GM-Tg-hg-T83450-Ag-2; GM-Tg-rg-T83450-Ag-1/ GM-Tg-rg-T83450-Ag-2;
GM-Tg-mg-T83450-Ag-1/ GM-Tg-mg-T83450-Ag-2; GM-Tg-cynog-T83450-Ag-1/ GM-Tg-cynog-T83450-Ag-2;
GM-Tg-felg-T83450-Ag-1/ GM-Tg-felg-T83450-Ag-2; GM-Tg-cang-T83450-Ag-1/ GM-Tg-cang-T83450-Ag-2;
GM-Tg-bovg-T83450-Ag-1/ GM-Tg-bovg-T83450-Ag-2; GM-Tg-equg-T83450-Ag-1/ GM-Tg-equg-T83450-Ag-2
Products Name COL6A3 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name COL6A3
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine COL6A3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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