Recombinant multi-species PRMT5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PRMT5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes an enzyme that belongs to the methyltransferase family. The encoded protein catalyzes the transfer of methyl groups to the amino acid arginine, in target proteins that include histones, transcriptional elongation factors and the tumor suppressor p53. This gene plays a role in several cellular processes, including transcriptional regulation, and the assembly of small nuclear ribonucleoproteins. A pseudogene of this gene has been defined on chromosome 4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]
The Alternative Names of target: PRMT5,Protein arginine N-methyltransferase 5,PRMT5,72 kDa ICln-binding protein, Histone-arginine N-methyltransferase PRMT5, Jak-binding protein 1, Shk1 kinase-binding protein 1 homolog (SKB1 homolog, SKB1Hs),HSL7,JBP1,SKB1,IBP72,SKB1Hs,HRMT1L5

Target products collectionGo to PRMT5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T82665-Ab-1/ GM-Tg-hg-T82665-Ab-2 Human PRMT5 protein Human
GM-Tg-rg-T82665-Ab-1/ GM-Tg-rg-T82665-Ab-2 Rat PRMT5 protein Rat
GM-Tg-mg-T82665-Ab-1/ GM-Tg-mg-T82665-Ab-2 Mouse PRMT5 protein Mouse
GM-Tg-cynog-T82665-Ab-1/ GM-Tg-cynog-T82665-Ab-2 Cynomolgus/Rhesus macaque PRMT5 monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-T82665-Ab-1/ GM-Tg-felg-T82665-Ab-2 Feline PRMT5 protein Feline
GM-Tg-cang-T82665-Ab-1/ GM-Tg-cang-T82665-Ab-2 Canine PRMT5 protein Canine
GM-Tg-bovg-T82665-Ab-1/ GM-Tg-bovg-T82665-Ab-2 Bovine PRMT5 protein Bovine
GM-Tg-equg-T82665-Ab-1/ GM-Tg-equg-T82665-Ab-2 Equine PRMT5 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T82665-Ab-1/ GM-Tg-hg-T82665-Ab-2; GM-Tg-rg-T82665-Ab-1/ GM-Tg-rg-T82665-Ab-2;
GM-Tg-mg-T82665-Ab-1/ GM-Tg-mg-T82665-Ab-2; GM-Tg-cynog-T82665-Ab-1/ GM-Tg-cynog-T82665-Ab-2;
GM-Tg-felg-T82665-Ab-1/ GM-Tg-felg-T82665-Ab-2; GM-Tg-cang-T82665-Ab-1/ GM-Tg-cang-T82665-Ab-2;
GM-Tg-bovg-T82665-Ab-1/ GM-Tg-bovg-T82665-Ab-2; GM-Tg-equg-T82665-Ab-1/ GM-Tg-equg-T82665-Ab-2
Products Name PRMT5 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PRMT5
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PRMT5 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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