Recombinant multi-species RARG protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RARG protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a retinoic acid receptor that belongs to the nuclear hormone receptor family. Retinoic acid receptors (RARs) act as ligand-dependent transcriptional regulators. When bound to ligands, RARs activate transcription by binding as heterodimers to the retinoic acid response elements (RARE) found in the promoter regions of the target genes. In their unbound form, RARs repress transcription of their target genes. RARs are involved in various biological processes, including limb bud development, skeletal growth, and matrix homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
The Alternative Names of target: NR1B3,Nr1b3,Nuclear receptor subfamily 1 group B member 3,RAR-gamma,RARC,RARD,RARG,RARgamma,RARgamma2,Rarg,Retinoic acid receptor gamma

Target products collectionGo to RARG products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T82146-Ag-1/ GM-Tg-hg-T82146-Ag-2 Human RARG protein Human
GM-Tg-rg-T82146-Ag-1/ GM-Tg-rg-T82146-Ag-2 Rat RARG protein Rat
GM-Tg-mg-T82146-Ag-1/ GM-Tg-mg-T82146-Ag-2 Mouse RARG protein Mouse
GM-Tg-cynog-T82146-Ag-1/ GM-Tg-cynog-T82146-Ag-2 Cynomolgus/Rhesus macaque RARG protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T82146-Ag-1/ GM-Tg-felg-T82146-Ag-2 Feline RARG protein Feline
GM-Tg-cang-T82146-Ag-1/ GM-Tg-cang-T82146-Ag-2 Canine RARG protein Canine
GM-Tg-bovg-T82146-Ag-1/ GM-Tg-bovg-T82146-Ag-2 Bovine RARG protein Bovine
GM-Tg-equg-T82146-Ag-1/ GM-Tg-equg-T82146-Ag-2 Equine RARG protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T82146-Ag-1/ GM-Tg-hg-T82146-Ag-2; GM-Tg-rg-T82146-Ag-1/ GM-Tg-rg-T82146-Ag-2;
GM-Tg-mg-T82146-Ag-1/ GM-Tg-mg-T82146-Ag-2; GM-Tg-cynog-T82146-Ag-1/ GM-Tg-cynog-T82146-Ag-2;
GM-Tg-felg-T82146-Ag-1/ GM-Tg-felg-T82146-Ag-2; GM-Tg-cang-T82146-Ag-1/ GM-Tg-cang-T82146-Ag-2;
GM-Tg-bovg-T82146-Ag-1/ GM-Tg-bovg-T82146-Ag-2; GM-Tg-equg-T82146-Ag-1/ GM-Tg-equg-T82146-Ag-2
Products Name RARG protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name RARG
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RARG protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.