Recombinant multi-species Cdc7 Kinase/CDC7 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Cdc7 Kinase/CDC7 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a cell division cycle protein with kinase activity that is critical for the G1/S transition. The yeast homolog is also essential for initiation of DNA replication as cell division occurs. Overexpression of this gene product may be associated with neoplastic transformation for some tumors. Multiple alternatively spliced transcript variants that encode the same protein have been detected. [provided by RefSeq, Aug 2008]
The Alternative Names of target: CDC7,CDC7-related kinase,CDC7L1,Cdc7,Cdc7 Kinase,Cdc7l1,Cell division cycle 7-related protein kinase,HsCDC7,HsCdc7,Hsk1,huCDC7,huCdc7,muCdc7
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T81358-Ag-1/ GM-Tg-hg-T81358-Ag-2 | Human Cdc7 Kinase/CDC7 protein | Human |
| GM-Tg-rg-T81358-Ag-1/ GM-Tg-rg-T81358-Ag-2 | Rat Cdc7 Kinase/CDC7 protein | Rat |
| GM-Tg-mg-T81358-Ag-1/ GM-Tg-mg-T81358-Ag-2 | Mouse Cdc7 Kinase/CDC7 protein | Mouse |
| GM-Tg-cynog-T81358-Ag-1/ GM-Tg-cynog-T81358-Ag-2 | Cynomolgus/Rhesus macaque Cdc7 Kinase/CDC7 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T81358-Ag-1/ GM-Tg-felg-T81358-Ag-2 | Feline Cdc7 Kinase/CDC7 protein | Feline |
| GM-Tg-cang-T81358-Ag-1/ GM-Tg-cang-T81358-Ag-2 | Canine Cdc7 Kinase/CDC7 protein | Canine |
| GM-Tg-bovg-T81358-Ag-1/ GM-Tg-bovg-T81358-Ag-2 | Bovine Cdc7 Kinase/CDC7 protein | Bovine |
| GM-Tg-equg-T81358-Ag-1/ GM-Tg-equg-T81358-Ag-2 | Equine Cdc7 Kinase/CDC7 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-T81358-Ag-1/ GM-Tg-hg-T81358-Ag-2;
GM-Tg-rg-T81358-Ag-1/ GM-Tg-rg-T81358-Ag-2;
GM-Tg-mg-T81358-Ag-1/ GM-Tg-mg-T81358-Ag-2; GM-Tg-cynog-T81358-Ag-1/ GM-Tg-cynog-T81358-Ag-2; GM-Tg-felg-T81358-Ag-1/ GM-Tg-felg-T81358-Ag-2; GM-Tg-cang-T81358-Ag-1/ GM-Tg-cang-T81358-Ag-2; GM-Tg-bovg-T81358-Ag-1/ GM-Tg-bovg-T81358-Ag-2; GM-Tg-equg-T81358-Ag-1/ GM-Tg-equg-T81358-Ag-2 |
| Products Name | Cdc7 Kinase/CDC7 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | Cdc7 Kinase/CDC7 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Cdc7 Kinase/CDC7 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.