Recombinant multi-species TPT1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TPT1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a protein that is a regulator of cellular growth and proliferation. Its mRNA is highly structured and contains an oligopyrimidine tract (5'-TOP) in its 5' untranslated region that functions to repress its translation under quiescent conditions. The encoded protein is involved in a variety of cellular pathways, including apoptosis, protein synthesis and cell division. It binds to and stabilizes microtubules, and removal of this protein through phosphorylation is required for progression through mitotic and meiotic cell divisions. This gene is known to play a role in carcinogenesis, and is upregulated in some cancer cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2017]
The Alternative Names of target: Fortilin,HRF,Histamine-releasing factor (HRF),TCTP,TPT1,Tpt1,Translationally-controlled tumor protein,Trt,p02,p21,p23

Target products collectionGo to TPT1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T77473-Ag-1/ GM-Tg-hg-T77473-Ag-2 Human TPT1 protein Human
GM-Tg-rg-T77473-Ag-1/ GM-Tg-rg-T77473-Ag-2 Rat TPT1 protein Rat
GM-Tg-mg-T77473-Ag-1/ GM-Tg-mg-T77473-Ag-2 Mouse TPT1 protein Mouse
GM-Tg-cynog-T77473-Ag-1/ GM-Tg-cynog-T77473-Ag-2 Cynomolgus/Rhesus macaque TPT1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T77473-Ag-1/ GM-Tg-felg-T77473-Ag-2 Feline TPT1 protein Feline
GM-Tg-cang-T77473-Ag-1/ GM-Tg-cang-T77473-Ag-2 Canine TPT1 protein Canine
GM-Tg-bovg-T77473-Ag-1/ GM-Tg-bovg-T77473-Ag-2 Bovine TPT1 protein Bovine
GM-Tg-equg-T77473-Ag-1/ GM-Tg-equg-T77473-Ag-2 Equine TPT1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T77473-Ag-1/ GM-Tg-hg-T77473-Ag-2; GM-Tg-rg-T77473-Ag-1/ GM-Tg-rg-T77473-Ag-2;
GM-Tg-mg-T77473-Ag-1/ GM-Tg-mg-T77473-Ag-2; GM-Tg-cynog-T77473-Ag-1/ GM-Tg-cynog-T77473-Ag-2;
GM-Tg-felg-T77473-Ag-1/ GM-Tg-felg-T77473-Ag-2; GM-Tg-cang-T77473-Ag-1/ GM-Tg-cang-T77473-Ag-2;
GM-Tg-bovg-T77473-Ag-1/ GM-Tg-bovg-T77473-Ag-2; GM-Tg-equg-T77473-Ag-1/ GM-Tg-equg-T77473-Ag-2
Products Name TPT1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name TPT1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TPT1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.