Recombinant multi-species PRX5/Prx5/PRDX5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PRX5/Prx5/PRDX5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein interacts with peroxisome receptor 1 and plays an antioxidant protective role in different tissues under normal conditions and during inflammatory processes. The use of alternate transcription start sites is thought to result in transcript variants that use different in-frame translational start codons to generate isoforms that are targeted to the mitochondrion (isoform L) or peroxisome/cytoplasm (isoform S). Multiple related pseudogenes have been defined for this gene. [provided by RefSeq, Nov 2017]
The Alternative Names of target: ACR1,AOEB166,AOPP,Alu corepressor 1,Antioxidant enzyme B166 (AOEB166),Aoeb166,B166,HEL-S-55,Liver tissue 2D-page spot 71B,PLP,PMP20,PRDX5,PRDX6,PRX5,PRXV,Peroxiredoxin V (Prx-V),Peroxiredoxin-5,Peroxisomal antioxidant enzyme,Pmp20,Prdx5,Prdx6,Prx V,Prx5,PrxV,SBBI10,TPx type VI,Thioredoxin peroxidase PMP20,Thioredoxin-dependent peroxiredoxin 5,mitochondrial,prx-V
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Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-T77009-Ag-1/ GM-Tg-hg-T77009-Ag-2 | Human PRX5/Prx5/PRDX5 protein | Human |
GM-Tg-rg-T77009-Ag-1/ GM-Tg-rg-T77009-Ag-2 | Rat PRX5/Prx5/PRDX5 protein | Rat |
GM-Tg-mg-T77009-Ag-1/ GM-Tg-mg-T77009-Ag-2 | Mouse PRX5/Prx5/PRDX5 protein | Mouse |
GM-Tg-cynog-T77009-Ag-1/ GM-Tg-cynog-T77009-Ag-2 | Cynomolgus/Rhesus macaque PRX5/Prx5/PRDX5 protein | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-T77009-Ag-1/ GM-Tg-felg-T77009-Ag-2 | Feline PRX5/Prx5/PRDX5 protein | Feline |
GM-Tg-cang-T77009-Ag-1/ GM-Tg-cang-T77009-Ag-2 | Canine PRX5/Prx5/PRDX5 protein | Canine |
GM-Tg-bovg-T77009-Ag-1/ GM-Tg-bovg-T77009-Ag-2 | Bovine PRX5/Prx5/PRDX5 protein | Bovine |
GM-Tg-equg-T77009-Ag-1/ GM-Tg-equg-T77009-Ag-2 | Equine PRX5/Prx5/PRDX5 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. |
GM-Tg-hg-T77009-Ag-1/ GM-Tg-hg-T77009-Ag-2;
GM-Tg-rg-T77009-Ag-1/ GM-Tg-rg-T77009-Ag-2;
GM-Tg-mg-T77009-Ag-1/ GM-Tg-mg-T77009-Ag-2; GM-Tg-cynog-T77009-Ag-1/ GM-Tg-cynog-T77009-Ag-2; GM-Tg-felg-T77009-Ag-1/ GM-Tg-felg-T77009-Ag-2; GM-Tg-cang-T77009-Ag-1/ GM-Tg-cang-T77009-Ag-2; GM-Tg-bovg-T77009-Ag-1/ GM-Tg-bovg-T77009-Ag-2; GM-Tg-equg-T77009-Ag-1/ GM-Tg-equg-T77009-Ag-2 |
Products Name | PRX5/Prx5/PRDX5 protein |
Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
Target Name | PRX5/Prx5/PRDX5 |
Protein Sub-location | Introcelluar Protein |
Isotypes | Recombinant protein |
Expression platform | Mammalian cell |
Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
Tag | His |
Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PRX5/Prx5/PRDX5 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab
GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.