Recombinant multi-species JMJD1C protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine JMJD1C protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene interacts with thyroid hormone receptors and contains a jumonji domain. It is a candidate histone demethylase and is thought to be a coactivator for key transcription factors. It plays a role in the DNA-damage response pathway by demethylating the mediator of DNA damage checkpoint 1 (MDC1) protein, and is required for the survival of acute myeloid leukemia. Mutations in this gene are associated with Rett syndrome and intellectual disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
The Alternative Names of target: 5430433L24Rik,D630035I23Rik,JMJD1C,Jmjd1c,Jmjdic,Jumonji domain-containing protein 1C,KDM3C,Pr2,Probable JmjC domain-containing histone demethylation protein 2C,TRIP-8,TRIP-8),TRIP8,Thyroid receptor-interacting protein 8 (TR-interacting protein 8

Target products collectionGo to JMJD1C products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T75792-Ag-1/ GM-Tg-hg-T75792-Ag-2 Human JMJD1C protein Human
GM-Tg-rg-T75792-Ag-1/ GM-Tg-rg-T75792-Ag-2 Rat JMJD1C protein Rat
GM-Tg-mg-T75792-Ag-1/ GM-Tg-mg-T75792-Ag-2 Mouse JMJD1C protein Mouse
GM-Tg-cynog-T75792-Ag-1/ GM-Tg-cynog-T75792-Ag-2 Cynomolgus/Rhesus macaque JMJD1C protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T75792-Ag-1/ GM-Tg-felg-T75792-Ag-2 Feline JMJD1C protein Feline
GM-Tg-cang-T75792-Ag-1/ GM-Tg-cang-T75792-Ag-2 Canine JMJD1C protein Canine
GM-Tg-bovg-T75792-Ag-1/ GM-Tg-bovg-T75792-Ag-2 Bovine JMJD1C protein Bovine
GM-Tg-equg-T75792-Ag-1/ GM-Tg-equg-T75792-Ag-2 Equine JMJD1C protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T75792-Ag-1/ GM-Tg-hg-T75792-Ag-2; GM-Tg-rg-T75792-Ag-1/ GM-Tg-rg-T75792-Ag-2;
GM-Tg-mg-T75792-Ag-1/ GM-Tg-mg-T75792-Ag-2; GM-Tg-cynog-T75792-Ag-1/ GM-Tg-cynog-T75792-Ag-2;
GM-Tg-felg-T75792-Ag-1/ GM-Tg-felg-T75792-Ag-2; GM-Tg-cang-T75792-Ag-1/ GM-Tg-cang-T75792-Ag-2;
GM-Tg-bovg-T75792-Ag-1/ GM-Tg-bovg-T75792-Ag-2; GM-Tg-equg-T75792-Ag-1/ GM-Tg-equg-T75792-Ag-2
Products Name JMJD1C protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name JMJD1C
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine JMJD1C protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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