Recombinant multi-species TFAP2A/AP-2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TFAP2A/AP-2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. Defects in this gene are a cause of branchiooculofacial syndrome (BOFS). Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2009]
The Alternative Names of target: AP-2,AP-2 transcription factor,AP-2alpha,AP2-alpha,AP2TF,AP2alpha,Activating enhancer-binding protein 2-alpha,Activator protein 2 (AP-2),Ap-2 (a),Ap2,Ap2tf,BOFS,TFAP2,TFAP2A,Tcfap2a,Tfap2a,Transcription factor AP-2-alpha

Target products collectionGo to TFAP2A/AP-2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T71317-Ag-1/ GM-Tg-hg-T71317-Ag-2 Human TFAP2A/AP-2 protein Human
GM-Tg-rg-T71317-Ag-1/ GM-Tg-rg-T71317-Ag-2 Rat TFAP2A/AP-2 protein Rat
GM-Tg-mg-T71317-Ag-1/ GM-Tg-mg-T71317-Ag-2 Mouse TFAP2A/AP-2 protein Mouse
GM-Tg-cynog-T71317-Ag-1/ GM-Tg-cynog-T71317-Ag-2 Cynomolgus/Rhesus macaque TFAP2A/AP-2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T71317-Ag-1/ GM-Tg-felg-T71317-Ag-2 Feline TFAP2A/AP-2 protein Feline
GM-Tg-cang-T71317-Ag-1/ GM-Tg-cang-T71317-Ag-2 Canine TFAP2A/AP-2 protein Canine
GM-Tg-bovg-T71317-Ag-1/ GM-Tg-bovg-T71317-Ag-2 Bovine TFAP2A/AP-2 protein Bovine
GM-Tg-equg-T71317-Ag-1/ GM-Tg-equg-T71317-Ag-2 Equine TFAP2A/AP-2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T71317-Ag-1/ GM-Tg-hg-T71317-Ag-2; GM-Tg-rg-T71317-Ag-1/ GM-Tg-rg-T71317-Ag-2;
GM-Tg-mg-T71317-Ag-1/ GM-Tg-mg-T71317-Ag-2; GM-Tg-cynog-T71317-Ag-1/ GM-Tg-cynog-T71317-Ag-2;
GM-Tg-felg-T71317-Ag-1/ GM-Tg-felg-T71317-Ag-2; GM-Tg-cang-T71317-Ag-1/ GM-Tg-cang-T71317-Ag-2;
GM-Tg-bovg-T71317-Ag-1/ GM-Tg-bovg-T71317-Ag-2; GM-Tg-equg-T71317-Ag-1/ GM-Tg-equg-T71317-Ag-2
Products Name TFAP2A/AP-2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name TFAP2A/AP-2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TFAP2A/AP-2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.