Recombinant multi-species KMT5C protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine KMT5C protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
SUV420H2 and the related enzyme SUV420H1 (MIM 610881) function as histone methyltransferases that specifically trimethylate nucleosomal histone H4 (see MIM 602822) on lysine-20 (K20) (Schotta et al., 2004 [PubMed 15145825]).[supplied by OMIM, Dec 2009]
The Alternative Names of target: Histone-lysine N-methyltransferase KMT5C,KMT5C,Kmt5c,Lysine N-methyltransferase 5C,Lysine-specific methyltransferase 5C,SUV420H2,Suppressor of variegation 4-20 homolog 2 (Su(var)4-20 homolog 2,Suv4-20h2,Suv4-20h2),Suv420h2,[histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B,[histone H4]-lysine20 N-methyltransferase KMT5B
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Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-T68490-Ag-1/ GM-Tg-hg-T68490-Ag-2 | Human KMT5C protein | Human |
GM-Tg-rg-T68490-Ag-1/ GM-Tg-rg-T68490-Ag-2 | Rat KMT5C protein | Rat |
GM-Tg-mg-T68490-Ag-1/ GM-Tg-mg-T68490-Ag-2 | Mouse KMT5C protein | Mouse |
GM-Tg-cynog-T68490-Ag-1/ GM-Tg-cynog-T68490-Ag-2 | Cynomolgus/Rhesus macaque KMT5C protein | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-T68490-Ag-1/ GM-Tg-felg-T68490-Ag-2 | Feline KMT5C protein | Feline |
GM-Tg-cang-T68490-Ag-1/ GM-Tg-cang-T68490-Ag-2 | Canine KMT5C protein | Canine |
GM-Tg-bovg-T68490-Ag-1/ GM-Tg-bovg-T68490-Ag-2 | Bovine KMT5C protein | Bovine |
GM-Tg-equg-T68490-Ag-1/ GM-Tg-equg-T68490-Ag-2 | Equine KMT5C protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. |
GM-Tg-hg-T68490-Ag-1/ GM-Tg-hg-T68490-Ag-2;
GM-Tg-rg-T68490-Ag-1/ GM-Tg-rg-T68490-Ag-2;
GM-Tg-mg-T68490-Ag-1/ GM-Tg-mg-T68490-Ag-2; GM-Tg-cynog-T68490-Ag-1/ GM-Tg-cynog-T68490-Ag-2; GM-Tg-felg-T68490-Ag-1/ GM-Tg-felg-T68490-Ag-2; GM-Tg-cang-T68490-Ag-1/ GM-Tg-cang-T68490-Ag-2; GM-Tg-bovg-T68490-Ag-1/ GM-Tg-bovg-T68490-Ag-2; GM-Tg-equg-T68490-Ag-1/ GM-Tg-equg-T68490-Ag-2 |
Products Name | KMT5C protein |
Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
Target Name | KMT5C |
Protein Sub-location | Introcelluar Protein |
Isotypes | Recombinant protein |
Expression platform | Mammalian cell |
Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
Tag | His |
Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine KMT5C protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab
GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.