Recombinant multi-species IDO2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IDO2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Along with the enzymes encoded by the INDO (MIM 147435) and TDO2 (MIM 191070) genes, the enzyme encoded by the INDOL1 gene metabolizes tryptophan in the kynurenine pathway (Ball et al., 2007 [PubMed 17499941]).[supplied by OMIM, Feb 2011]
The Alternative Names of target: 3-dioxygenase 2,3-dioxygenase-like protein 1,C230043N17Rik,IDO-2,IDO2,INDOL1,Ido-2,Ido2,Indol1,Indoleamine 2,Indoleamine-pyrrole 2

Target products collectionGo to IDO2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T62266-Ag-1/ GM-Tg-hg-T62266-Ag-2 Human IDO2 protein Human
GM-Tg-rg-T62266-Ag-1/ GM-Tg-rg-T62266-Ag-2 Rat IDO2 protein Rat
GM-Tg-mg-T62266-Ag-1/ GM-Tg-mg-T62266-Ag-2 Mouse IDO2 protein Mouse
GM-Tg-cynog-T62266-Ag-1/ GM-Tg-cynog-T62266-Ag-2 Cynomolgus/Rhesus macaque IDO2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T62266-Ag-1/ GM-Tg-felg-T62266-Ag-2 Feline IDO2 protein Feline
GM-Tg-cang-T62266-Ag-1/ GM-Tg-cang-T62266-Ag-2 Canine IDO2 protein Canine
GM-Tg-bovg-T62266-Ag-1/ GM-Tg-bovg-T62266-Ag-2 Bovine IDO2 protein Bovine
GM-Tg-equg-T62266-Ag-1/ GM-Tg-equg-T62266-Ag-2 Equine IDO2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T62266-Ag-1/ GM-Tg-hg-T62266-Ag-2; GM-Tg-rg-T62266-Ag-1/ GM-Tg-rg-T62266-Ag-2;
GM-Tg-mg-T62266-Ag-1/ GM-Tg-mg-T62266-Ag-2; GM-Tg-cynog-T62266-Ag-1/ GM-Tg-cynog-T62266-Ag-2;
GM-Tg-felg-T62266-Ag-1/ GM-Tg-felg-T62266-Ag-2; GM-Tg-cang-T62266-Ag-1/ GM-Tg-cang-T62266-Ag-2;
GM-Tg-bovg-T62266-Ag-1/ GM-Tg-bovg-T62266-Ag-2; GM-Tg-equg-T62266-Ag-1/ GM-Tg-equg-T62266-Ag-2
Products Name IDO2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name IDO2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IDO2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.