Recombinant multi-species CDK7 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CDK7 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle. [provided by RefSeq, Jul 2008]
The Alternative Names of target: CDK7,Cyclin-dependent kinase 7,39 kDa protein kinase (p39 Mo15), CDK-activating kinase 1, Cell division protein kinase 7, Serine/threonine-protein kinase 1, TFIIH basal transcription factor complex kinase subunit,CAK,CAK1,HCAK,MO15,STK1,CDKN7,p39MO15

Target products collectionGo to CDK7 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T58449-Ab-1/ GM-Tg-hg-T58449-Ab-2 Human CDK7 protein Human
GM-Tg-rg-T58449-Ab-1/ GM-Tg-rg-T58449-Ab-2 Rat CDK7 protein Rat
GM-Tg-mg-T58449-Ab-1/ GM-Tg-mg-T58449-Ab-2 Mouse CDK7 protein Mouse
GM-Tg-cynog-T58449-Ab-1/ GM-Tg-cynog-T58449-Ab-2 Cynomolgus/Rhesus macaque CDK7 monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-T58449-Ab-1/ GM-Tg-felg-T58449-Ab-2 Feline CDK7 protein Feline
GM-Tg-cang-T58449-Ab-1/ GM-Tg-cang-T58449-Ab-2 Canine CDK7 protein Canine
GM-Tg-bovg-T58449-Ab-1/ GM-Tg-bovg-T58449-Ab-2 Bovine CDK7 protein Bovine
GM-Tg-equg-T58449-Ab-1/ GM-Tg-equg-T58449-Ab-2 Equine CDK7 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T58449-Ab-1/ GM-Tg-hg-T58449-Ab-2; GM-Tg-rg-T58449-Ab-1/ GM-Tg-rg-T58449-Ab-2;
GM-Tg-mg-T58449-Ab-1/ GM-Tg-mg-T58449-Ab-2; GM-Tg-cynog-T58449-Ab-1/ GM-Tg-cynog-T58449-Ab-2;
GM-Tg-felg-T58449-Ab-1/ GM-Tg-felg-T58449-Ab-2; GM-Tg-cang-T58449-Ab-1/ GM-Tg-cang-T58449-Ab-2;
GM-Tg-bovg-T58449-Ab-1/ GM-Tg-bovg-T58449-Ab-2; GM-Tg-equg-T58449-Ab-1/ GM-Tg-equg-T58449-Ab-2
Products Name CDK7 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CDK7
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CDK7 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.