Recombinant multi-species HOXA11 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HOXA11 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is involved in the regulation of uterine development and is required for female fertility. Mutations in this gene can cause radio-ulnar synostosis with amegakaryocytic thrombocytopenia. [provided by RefSeq, Jul 2008]
The Alternative Names of target: HOXA11,Homeobox protein Hox-A11,Homeobox protein Hox-1I,HOX1,HOX1I,RUSAT1
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Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-T56290-Ab-1/ GM-Tg-hg-T56290-Ab-2 | Human HOXA11 protein | Human |
GM-Tg-rg-T56290-Ab-1/ GM-Tg-rg-T56290-Ab-2 | Rat HOXA11 protein | Rat |
GM-Tg-mg-T56290-Ab-1/ GM-Tg-mg-T56290-Ab-2 | Mouse HOXA11 protein | Mouse |
GM-Tg-cynog-T56290-Ab-1/ GM-Tg-cynog-T56290-Ab-2 | Cynomolgus/Rhesus macaque HOXA11 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-T56290-Ab-1/ GM-Tg-felg-T56290-Ab-2 | Feline HOXA11 protein | Feline |
GM-Tg-cang-T56290-Ab-1/ GM-Tg-cang-T56290-Ab-2 | Canine HOXA11 protein | Canine |
GM-Tg-bovg-T56290-Ab-1/ GM-Tg-bovg-T56290-Ab-2 | Bovine HOXA11 protein | Bovine |
GM-Tg-equg-T56290-Ab-1/ GM-Tg-equg-T56290-Ab-2 | Equine HOXA11 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. |
GM-Tg-hg-T56290-Ab-1/ GM-Tg-hg-T56290-Ab-2;
GM-Tg-rg-T56290-Ab-1/ GM-Tg-rg-T56290-Ab-2;
GM-Tg-mg-T56290-Ab-1/ GM-Tg-mg-T56290-Ab-2; GM-Tg-cynog-T56290-Ab-1/ GM-Tg-cynog-T56290-Ab-2; GM-Tg-felg-T56290-Ab-1/ GM-Tg-felg-T56290-Ab-2; GM-Tg-cang-T56290-Ab-1/ GM-Tg-cang-T56290-Ab-2; GM-Tg-bovg-T56290-Ab-1/ GM-Tg-bovg-T56290-Ab-2; GM-Tg-equg-T56290-Ab-1/ GM-Tg-equg-T56290-Ab-2 |
Products Name | HOXA11 protein |
Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
Target Name | HOXA11 |
Protein Sub-location | Introcelluar Protein |
Isotypes | Recombinant protein |
Expression platform | Mammalian cell |
Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
Tag | His |
Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HOXA11 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab
GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.