Recombinant multi-species Cytokeratin 19/KRT19 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Cytokeratin 19/KRT19 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2008]
The Alternative Names of target: CK-19,CK19,Cytokeratin 19,Cytokeratin-19 (CK-19),EndoC,K19,K1CS,KRT19,Ka19,Keratin,Keratin-19 (K19),Krt-1.19,Krt1-19,Krt19,type I cytoskeletal 19

Target products collectionGo to Cytokeratin 19/KRT19 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T54461-Ag-1/ GM-Tg-hg-T54461-Ag-2 Human Cytokeratin 19/KRT19 protein Human
GM-Tg-rg-T54461-Ag-1/ GM-Tg-rg-T54461-Ag-2 Rat Cytokeratin 19/KRT19 protein Rat
GM-Tg-mg-T54461-Ag-1/ GM-Tg-mg-T54461-Ag-2 Mouse Cytokeratin 19/KRT19 protein Mouse
GM-Tg-cynog-T54461-Ag-1/ GM-Tg-cynog-T54461-Ag-2 Cynomolgus/Rhesus macaque Cytokeratin 19/KRT19 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T54461-Ag-1/ GM-Tg-felg-T54461-Ag-2 Feline Cytokeratin 19/KRT19 protein Feline
GM-Tg-cang-T54461-Ag-1/ GM-Tg-cang-T54461-Ag-2 Canine Cytokeratin 19/KRT19 protein Canine
GM-Tg-bovg-T54461-Ag-1/ GM-Tg-bovg-T54461-Ag-2 Bovine Cytokeratin 19/KRT19 protein Bovine
GM-Tg-equg-T54461-Ag-1/ GM-Tg-equg-T54461-Ag-2 Equine Cytokeratin 19/KRT19 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T54461-Ag-1/ GM-Tg-hg-T54461-Ag-2; GM-Tg-rg-T54461-Ag-1/ GM-Tg-rg-T54461-Ag-2;
GM-Tg-mg-T54461-Ag-1/ GM-Tg-mg-T54461-Ag-2; GM-Tg-cynog-T54461-Ag-1/ GM-Tg-cynog-T54461-Ag-2;
GM-Tg-felg-T54461-Ag-1/ GM-Tg-felg-T54461-Ag-2; GM-Tg-cang-T54461-Ag-1/ GM-Tg-cang-T54461-Ag-2;
GM-Tg-bovg-T54461-Ag-1/ GM-Tg-bovg-T54461-Ag-2; GM-Tg-equg-T54461-Ag-1/ GM-Tg-equg-T54461-Ag-2
Products Name Cytokeratin 19/KRT19 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name Cytokeratin 19/KRT19
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Cytokeratin 19/KRT19 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.