Recombinant multi-species TBXT protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TBXT protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called the T-box, and effects transcription of genes required for mesoderm formation and differentiation. The protein is localized to notochord-derived cells. Variation in this gene was associated with susceptibility to neural tube defects and chordoma. A mutation in this gene was found in a family with sacral agenesis with vertebral anomalies. [provided by RefSeq, Sep 2018]
The Alternative Names of target: Bra,Brachyury protein,D17Mit170,Low,Lr,Protein T,SAVA,T,T-box transcription factor T,T1,TBXT,TFT,Tbxt,Tl2,Tl3,brachyury,cou,me75

Target products collectionGo to TBXT products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T54093-Ag-1/ GM-Tg-hg-T54093-Ag-2 Human TBXT protein Human
GM-Tg-rg-T54093-Ag-1/ GM-Tg-rg-T54093-Ag-2 Rat TBXT protein Rat
GM-Tg-mg-T54093-Ag-1/ GM-Tg-mg-T54093-Ag-2 Mouse TBXT protein Mouse
GM-Tg-cynog-T54093-Ag-1/ GM-Tg-cynog-T54093-Ag-2 Cynomolgus/Rhesus macaque TBXT protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T54093-Ag-1/ GM-Tg-felg-T54093-Ag-2 Feline TBXT protein Feline
GM-Tg-cang-T54093-Ag-1/ GM-Tg-cang-T54093-Ag-2 Canine TBXT protein Canine
GM-Tg-bovg-T54093-Ag-1/ GM-Tg-bovg-T54093-Ag-2 Bovine TBXT protein Bovine
GM-Tg-equg-T54093-Ag-1/ GM-Tg-equg-T54093-Ag-2 Equine TBXT protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T54093-Ag-1/ GM-Tg-hg-T54093-Ag-2; GM-Tg-rg-T54093-Ag-1/ GM-Tg-rg-T54093-Ag-2;
GM-Tg-mg-T54093-Ag-1/ GM-Tg-mg-T54093-Ag-2; GM-Tg-cynog-T54093-Ag-1/ GM-Tg-cynog-T54093-Ag-2;
GM-Tg-felg-T54093-Ag-1/ GM-Tg-felg-T54093-Ag-2; GM-Tg-cang-T54093-Ag-1/ GM-Tg-cang-T54093-Ag-2;
GM-Tg-bovg-T54093-Ag-1/ GM-Tg-bovg-T54093-Ag-2; GM-Tg-equg-T54093-Ag-1/ GM-Tg-equg-T54093-Ag-2
Products Name TBXT protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name TBXT
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TBXT protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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