Recombinant multi-species Cryptochrome 2/CRY2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Cryptochrome 2/CRY2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2014]
The Alternative Names of target: CRY2,Cry2,Cryptochrome 2,Cryptochrome-2,D130054K12Rik,HCRY2,PHLL2
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T51908-Ag-1/ GM-Tg-hg-T51908-Ag-2 | Human Cryptochrome 2/CRY2 protein | Human |
| GM-Tg-rg-T51908-Ag-1/ GM-Tg-rg-T51908-Ag-2 | Rat Cryptochrome 2/CRY2 protein | Rat |
| GM-Tg-mg-T51908-Ag-1/ GM-Tg-mg-T51908-Ag-2 | Mouse Cryptochrome 2/CRY2 protein | Mouse |
| GM-Tg-cynog-T51908-Ag-1/ GM-Tg-cynog-T51908-Ag-2 | Cynomolgus/Rhesus macaque Cryptochrome 2/CRY2 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T51908-Ag-1/ GM-Tg-felg-T51908-Ag-2 | Feline Cryptochrome 2/CRY2 protein | Feline |
| GM-Tg-cang-T51908-Ag-1/ GM-Tg-cang-T51908-Ag-2 | Canine Cryptochrome 2/CRY2 protein | Canine |
| GM-Tg-bovg-T51908-Ag-1/ GM-Tg-bovg-T51908-Ag-2 | Bovine Cryptochrome 2/CRY2 protein | Bovine |
| GM-Tg-equg-T51908-Ag-1/ GM-Tg-equg-T51908-Ag-2 | Equine Cryptochrome 2/CRY2 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-T51908-Ag-1/ GM-Tg-hg-T51908-Ag-2;
GM-Tg-rg-T51908-Ag-1/ GM-Tg-rg-T51908-Ag-2;
GM-Tg-mg-T51908-Ag-1/ GM-Tg-mg-T51908-Ag-2; GM-Tg-cynog-T51908-Ag-1/ GM-Tg-cynog-T51908-Ag-2; GM-Tg-felg-T51908-Ag-1/ GM-Tg-felg-T51908-Ag-2; GM-Tg-cang-T51908-Ag-1/ GM-Tg-cang-T51908-Ag-2; GM-Tg-bovg-T51908-Ag-1/ GM-Tg-bovg-T51908-Ag-2; GM-Tg-equg-T51908-Ag-1/ GM-Tg-equg-T51908-Ag-2 |
| Products Name | Cryptochrome 2/CRY2 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | Cryptochrome 2/CRY2 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Cryptochrome 2/CRY2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
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entities. Leveraging the sophisticated
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characterized by high binding affinity,
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Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.