Recombinant multi-species GATA4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GATA4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. This protein is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function, and is necessary for normal testicular development. Mutations in this gene have been associated with cardiac septal defects. Additionally, alterations in gene expression have been associated with several cancer types. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
The Alternative Names of target: ASD2,GATA-binding factor 4,GATA4,Gata-4,Gata4,TACHD,TOF,Transcription factor GATA-4,VSD1

Target products collectionGo to GATA4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T51817-Ag-1/ GM-Tg-hg-T51817-Ag-2 Human GATA4 protein Human
GM-Tg-rg-T51817-Ag-1/ GM-Tg-rg-T51817-Ag-2 Rat GATA4 protein Rat
GM-Tg-mg-T51817-Ag-1/ GM-Tg-mg-T51817-Ag-2 Mouse GATA4 protein Mouse
GM-Tg-cynog-T51817-Ag-1/ GM-Tg-cynog-T51817-Ag-2 Cynomolgus/Rhesus macaque GATA4 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T51817-Ag-1/ GM-Tg-felg-T51817-Ag-2 Feline GATA4 protein Feline
GM-Tg-cang-T51817-Ag-1/ GM-Tg-cang-T51817-Ag-2 Canine GATA4 protein Canine
GM-Tg-bovg-T51817-Ag-1/ GM-Tg-bovg-T51817-Ag-2 Bovine GATA4 protein Bovine
GM-Tg-equg-T51817-Ag-1/ GM-Tg-equg-T51817-Ag-2 Equine GATA4 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T51817-Ag-1/ GM-Tg-hg-T51817-Ag-2; GM-Tg-rg-T51817-Ag-1/ GM-Tg-rg-T51817-Ag-2;
GM-Tg-mg-T51817-Ag-1/ GM-Tg-mg-T51817-Ag-2; GM-Tg-cynog-T51817-Ag-1/ GM-Tg-cynog-T51817-Ag-2;
GM-Tg-felg-T51817-Ag-1/ GM-Tg-felg-T51817-Ag-2; GM-Tg-cang-T51817-Ag-1/ GM-Tg-cang-T51817-Ag-2;
GM-Tg-bovg-T51817-Ag-1/ GM-Tg-bovg-T51817-Ag-2; GM-Tg-equg-T51817-Ag-1/ GM-Tg-equg-T51817-Ag-2
Products Name GATA4 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name GATA4
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GATA4 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.