Recombinant multi-species QPCT protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine QPCT protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes human pituitary glutaminyl cyclase, which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86% identical to that of bovine glutaminyl cyclase. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 5730422A13Rik,GCT,Glutaminyl cyclase (QC,Glutaminyl-peptide cyclotransferase,Glutaminyl-tRNA cyclotransferase,Glutamyl cyclase (EC),QC,QPCT,Qpct,Qpctl1,RGD1562284,sQC,sQC)

Target products collectionGo to QPCT products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T46245-Ag-1/ GM-Tg-hg-T46245-Ag-2 Human QPCT protein Human
GM-Tg-rg-T46245-Ag-1/ GM-Tg-rg-T46245-Ag-2 Rat QPCT protein Rat
GM-Tg-mg-T46245-Ag-1/ GM-Tg-mg-T46245-Ag-2 Mouse QPCT protein Mouse
GM-Tg-cynog-T46245-Ag-1/ GM-Tg-cynog-T46245-Ag-2 Cynomolgus/Rhesus macaque QPCT protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T46245-Ag-1/ GM-Tg-felg-T46245-Ag-2 Feline QPCT protein Feline
GM-Tg-cang-T46245-Ag-1/ GM-Tg-cang-T46245-Ag-2 Canine QPCT protein Canine
GM-Tg-bovg-T46245-Ag-1/ GM-Tg-bovg-T46245-Ag-2 Bovine QPCT protein Bovine
GM-Tg-equg-T46245-Ag-1/ GM-Tg-equg-T46245-Ag-2 Equine QPCT protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T46245-Ag-1/ GM-Tg-hg-T46245-Ag-2; GM-Tg-rg-T46245-Ag-1/ GM-Tg-rg-T46245-Ag-2;
GM-Tg-mg-T46245-Ag-1/ GM-Tg-mg-T46245-Ag-2; GM-Tg-cynog-T46245-Ag-1/ GM-Tg-cynog-T46245-Ag-2;
GM-Tg-felg-T46245-Ag-1/ GM-Tg-felg-T46245-Ag-2; GM-Tg-cang-T46245-Ag-1/ GM-Tg-cang-T46245-Ag-2;
GM-Tg-bovg-T46245-Ag-1/ GM-Tg-bovg-T46245-Ag-2; GM-Tg-equg-T46245-Ag-1/ GM-Tg-equg-T46245-Ag-2
Products Name QPCT protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name QPCT
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine QPCT protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.